SIR?As one who has been using spinal anaesthesia of late, it would be of interest to hear from other users what disadvantages they have experienced in its use, and especially whether they have employed it in children, and of what age and for what purposes. One would think that for stone in children it would be ideal, as the relaxation is so complete, but I believe text-books caution surgeons ag...

Fatty accumulation per se does not appear to affect liver function; however, interest has recently renewed to fatty liver because of the clinical relevance of non alcoholic steato-hepatitis (NASH) and for the increased risk of post-transplant failure in grafted livers with steatosis. Clinical and experimental studies have doubtless demonstrated that oxidative stress ensues in steatotic livers. ...

In this region of the electromagnetic spectrum there is some important astrophysics, such as the spectral peak of the alleged 2.7" K isotropic cosmic black-body radiation, thermal radiation by interstellar and possibly intergalactic dust, as well as intense radiation from galactic centers, and doubtless other information concerning the early history of an evolving universe. An experiment carrie...

Background: The brain is primarily a massively parallel computer and the brainstem is no exception. Doubtless of vital importance to life, the brainstem centres controlling respiration continue to evade precise identification. Rett syndrome (RTT) is an interesting neurodevelopmental disorder that produces characteristic neurological and behavioural features. Clinical features include autistic t...

Using the Yguazú-a three-dimensional hydrodynamic code, we have computed a set of numerical simulations of heavy, supersonic, radiatively cooling jets including variabilities in both the ejection direction (precession) and the jet velocity (intermittence). In order to investigate the effects of jet rotation on the shape of the line profiles, we also introduce an initial toroidal rotation veloci...

Introductory Primary diverticula of the small and large intestine are acquired by a process of herniation of the mucosa through the muscle coat of the bowel and are an affection of middle age and later. The mechanism, as with herniation through the abdominal parieties, is exceedingly complex and little understood. It is generally agreed that two basic factors are concerned-pressure within the c...

Mucins are of major interest in cell biology, not only are they highly over-expressed in many adenocarcinomas (up to 40-fold increase), but also have important physiological function, and probably more to be determined (1-3). There is much information available on mucins - doubtless because of their unusual structure being heavily glycosylated, but also containing a repeat region rich in the am...

this point is it really clear that with the Chirurgia, the opposite principle operated. The unwary reader might also assume that only asterisked words in the text have been corrected, though the notes reveal other unsignalled emendations, based on "the Latin" (i.e. Karl Sudhoff's not entirely satisfactory edition). Details such as the sudden leap from fol. 225r to fol. 266r on p. 63 (II, III) a...

Overconfidence refers to the exaggerated beliefs that one might have about his own personal abilities. This phenomenon seems to be pervasive and it could help explaining several economic paradoxes. Still the profession has failed to produce conclusive evidence about overconfident behavior using market data. Most of the evidence that shows that people are overconfident comes from either psycholo...

INTRODUCTION The splenic involvement is common in sarcoidosis, but its real frequency is still obscure depending doubtless on the method of splenomegaly detection. Splenomegaly may be accompanied with pain or anemia, leucopenia and thrombocytopenia. OBJECTIVE The aim of this study was to investigate the frequency of splenomegaly related to clinical characteristics of sarcoidosis and to solve ...