in recent years there has been considerable interest in the synthesis and separation of enantiomers of organic compounds especially because of their importance in the biochemistry and pharmaceutical industry. high-performance liquid chromatography is a very useful method for the direct separation of enantiomers. however, about 30−40 years ago, commercially available chiral stationary phases wer...

background: motor vehicle traffic injuries are indeed one of the most important worldwide health problems. opioids can induce a depressant effect on the central nervous system which may increase the risk of traffic accidents. this cross-sectional case-control study was conducted in marvdasht, iran to investigate the presence of drugs in hospitalized non-fatally injured drivers of motor vehicles...

background and objective: diabetes mellitus is one of the main problems in health systems in the world. diabetic foot infections (dfi) is one of the main complications and the most cause  of non-traumatic lower limb amputation .this study aimed to determine the prevalence of bacteria involved in dfi and their antibiotic resistance in patients with dfi diagnosis. patients and methods: this desc...

recently, there have been more reports of cardiac valve infections due to the increasing number of intravenous (iv) drug abusers and chronic renal failure patients. among cardiac valves, tricuspid valve is most commonly affected in the course of endocarditis. appropriate management of these patients is a challenging and controversial issue in the field of cardiac surgery. treatment options in s...

this commentary explores the implications of increased social media marketing by drug manufacturers, based on findings in hyosun kim’s article of the major themes in recent food and drug administration (fda) warning letters and notices of violation regarding online direct-to-consumer promotions of pharmaceuticals. kim’s rigorous analysis of fda letters over a 10-year span highlights a relative ...

background rational prescription is a considerable issue which must be paid more attention to assess the behavior of prescribers. the aim of this study was to examine factors affecting family physicians’ drug prescribing.   methods we carried out a retrospective cross-sectional study in khuzestan province, iran in 2011. nine hundred eighty-six prescriptions of 421 family physicians (including 3...

background methamphetamine (ma) is a highly addictive stimulant which has destructive effects. there is also evidence that methamphetamine use in some females, partly is due to their desire to lose weight. the purpose of this study was to determine the association between family flexibility, food preoccupation and body image among crystal abuser women. objectives this study tried to evaluate wh...

results: most addict patients had a medium level of education. improvement in knowledge, attitude and practice (kap) of patients after intervention was observed as follows; decreasing kap in poor level (2.8% vs. 30.6%), (3% vs. 50%), (25% vs. 80.6%), respectively; also, increasing kap in fair level (7% vs. 55.6 %), (15% vs. 15%), (19% vs. 7%), respectively and increasing kap in satisfactory lev...

background: drug use evaluation (due) aims at improving the patients’ care. studying the administration pattern of intravenous immunoglobulin (ivig) is an important research topic due to its significant role in the treatment and controlling of many disorders, high prices, and limited availability of this drug. methods: this observational cross-sectional study was conducted at shahid sadoughi ho...