OBJECTIVE To study the effects of supplementation with organic and inorganic chromium on glucose tolerance, serum lipids, and drug dosage in type 2 diabetes patients, in the hope of finding a better and more economical method of control. METHODS Seventy eight type 2 diabetes patients were divided randomly into two groups and given Brewer's yeast (23.3ug Cr/day), and CrCl3 (200ug Cr/day) seque...

Therapeutic drug monitoring (TDM) is defined as the clinical laboratory measurement of the levels of drugs in plasma, serum or blood of patients that, with appropriate medical interpretation, will directly influence drug prescribing procedures [1]. TDM is also referred to as the individualization of drug dosage by maintaining plasma or blood drug concentrations within a targeted therapeutic ran...

introduction: drug utilization evaluation (due) studies are designed to assess drug usage appropriateness. dues have traditionally focused on drugs with high price tags, complicated dosage schedules, narrow therapeutic indices and regular side effects. the primary goal of the present study is to evaluate imipenem usage in bone marrow transplantation (bmt) wards. methods: the study was a prospec...

a clinical study was made on epileptic patients in the diagnostic department of the tehran school of dentistry. the results showed that not all of the epileptic patients who are under control with phenytoin develop hyperplasia, and those who do not care about their oral health and hygiene will be afflicted by hyperplasia of gum. on the basis of patients, records gingival hyperplasia in most pat...

The use of hydrophilic polymers from natural origin. Especially the polysaccharides have been focus current research activity in design matrix device due to their non toxic, biocompatible, biodegradable nature and broad regulatory acceptance. A large number such as Carboxymethyl starch, Xanthan gum, Hydroxy propyl methyl cellulose (HPMC), Sodium Alginate etc, used matrices investigate release b...

      The objective of present research was to design, evaluate and compare drug release from two different dosage forms in pulsatile drug delivery system (DDS) for Metoprolol tartarate (MT) as tablet and capsule. Pulsatile systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal del...

an oral suspension could a suitable dosage form for the geriatric patients. the calcium alginate coated ion exchange resinate of propranolol hydrochloride were prepared using amberlite ir-120 by solvent evaporation. microcapsules of propranolol hydrochloride resinate were prepared by solvent evaporation technique,the suspensions were prepared by using deionised water as the vehicle. methyl cell...

The design, preparation and application of three-dimensional (3D) printed structures have gained appreciable interest in recent times, particularly for drug dosage development. In this study, the electrohydrodynamic (EHD) printing technique was developed to fabricate aligned-fiber antibiotic (tetracycline hydrochloride, TE-HCL) patches using polycaprolactone (PCL), polyvinyl pyrrolidone (PVP) a...

Responsiveness to antihypertensive medications was investigated cross-sectionally in 559 individuals comprising all treated hypertensive patients identified within a representative sample (n = 3,532, aged 40-70 years) of the Jewish population in Israel. A rate of dosage score (a summed ranking of dosages of all drugs taken) of two or more increased significantly with increasing levels of body m...

Community-acquired pneumonia (CAP) is a common infectious disease in children. Rational drug use (RDU) is an important approach to reducing the disease burden and mortality rate of CAP in children. There are no monitoring indicators for assessing RDU in children. This study aimed to develop a set of indicators to assess RDU to treat CAP in children in hospitals and clinics using a modified Delp...