نتایج جستجو برای: drug nanocarriers

تعداد نتایج: 590981  

2013
Brian C. Baumann Gary D. Kao Abdullah Mahmud Takamasa Harada Joe Swift Christina Chapman Xiangsheng Xu Dennis E. Discher Jay F. Dorsey

Glioblastoma multiforme (GBM) is a common, usually lethal disease with a median survival of only ~15 months. It has proven resistant in clinical trials to chemotherapeutic agents such as paclitaxel that are highly effective in vitro, presumably because of impaired drug delivery across the tumor's blood-brain barrier (BBB). In an effort to increase paclitaxel delivery across the tumor BBB, we li...

2018
Katsutoshi Kokubun Sachiko Matsumura Masako Yudasaka Sumio Iijima Kiyotaka Shiba

Introduction Inorganic materials are widely used in medical devices, such as artificial hearts, vessels, and joints, in stents, and as nanocarriers for drug-delivery systems. Carbon nanomaterials are of particular interest due to their biological inertness and their capability to accommodate molecules. Several attempts have been proposed, in which carbon nanomaterials are used as nanocarriers f...

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