Drug overdose continues to be a major cause of death, especially among young people in Europe, with recent data showing that it accounts for approximately 4% of all deaths in adult males under 40 years of age (Eurostat, 2012). European countries have implemented a variety of approaches in their attempt to reduce overdose deaths at the national level using evidence-based interventions drawing on...

Two very different cases of overdose with tranylcypromine are presented. One clinical case involving the ingestion of 400 mg tranylcypromine with suicidal intention and one fatality with a suspicion of possible tranylcypromine overdose were examined. Both cases showed similar blood concentrations (0.5 and 0.7 mg/L, respectively), but the clinical case exhibited only mild symptoms of intoxicatio...

Fatal opioid overdose, the leading cause of injury death in the USA, is regularly described as an epidemic. The response to the overdose crisis, however, has largely failed to utilise many of the public health tools that have proven effective in combating epidemics. Chief among these is the systematic and timely use of data by public health officials to track outbreaks and effectively target in...

Introduction Drug overdoses are an increasingly serious problem in the United States and worldwide. The CDC estimates that 47,055 drug overdose deaths occurred in the United States in 2014, 61% of which involved opioids (including heroin, pain relievers such as oxycodone, and synthetics).1 Overdose deaths involving opioids increased 3-fold from 2000 to 2014.1 These statistics motivate public he...

benzodiazepine overdose is the most commonly encountered drug overdose in iran. it has been reported by many authors that flumazenil possesses highly specific antagonistic activity on central benzodiazepine receptors. we conducted a prospective study on 150 patients brought to the toxicology emergency ward in loghman-hakim hospital with benzodiazepine overdose to assess the efficacy of flumazen...

Sildenafil is a selective phosphodiesterase type-5 inhibitor that increasingly used to treat pulmonary hypertension (PH) in neonates. Only little known about the relation between dose of sildenafil, plasma concentrations, and degree toxicity. Here, we present young infant with congenital diaphragmatic hernia PH who received an unintentional 10-fold overdose oral sildenafil for 6 consecutive day...

The past fortnight has seen the release of alarming new fi gures about drug overdose in England and Wales, together with a report damning the UK Government’s approaches to drug addiction. Prime Minister David Cameron should take heed. Both legal and illegal drugs cause many deaths in the UK. The National Offi ce for Statistics reports that 2597 people died from overdoses in 2012—1496 cases were...

aUniversity of Kentucky, College of Public Health, Lexington, KY bNew York City Department of Health and Mental Hygiene, New York, NY cNorth Carolina Division of Public Health, Raleigh, NC dKansas Department of Health and Environment, Topeka, KS eUtah Department of Health Violence and Injury Prevention Program, Salt Lake City, UT fMaryland Department of Health & Mental Hygiene, Baltimore, MD gM...

For more on breastfeeding and the Affordable Care Act see http://www.cdc.gov/ breastfeeding/pdf/BFGuide-508.PDF Breastmilk makes the world healthier, smarter, and more equal: these are the conclusions of a new Lancet Series on breastfeeding. The deaths of 823 000 children and 20 000 mothers each year could be averted through universal breastfe eding, along with economic savings of US$300 billio...