it is possible to alter the permeability of ethyl cellulose membrane with certain materials such as surfactants. in this study the effect of surfactant concentration and different hlb values on the release rate of atenolol from ethyl cellulose-coated tablets was evaluated. the results showed that when the concentration of surfactant increased, the rate of drug release also increased. the kineti...

the present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. fourier transform infrared spectroscopy (ftir) and differential scannin...

the objective of the present investigation was to design a sustained release floating microcapsules of theophylline using two polymers of different permeability characteristics; eudragit rl 100 (eu rl) and cellulose acetate butyrate (cab) using the oil-in-oil emulsion solvent evaporation method. polymers were used separately and in combination to prepare different microcapsules. the effect of d...

     The purpose of this work was to develop once daily sustained release (SR) matrix tablets of naproxen, an anti-inflammatory agent. The tablets were prepared by wet granulation method along with hydrophilic matrix materials like Methocel K 15M CR and Methocel K 100M CR. The granules were evaluated for bulk density, angle of repose, compressibility index, total porosity and drug content. The ...

in this paper, carbon nanotubes (cnts) were added into chitosan (cs) hydrogels in the form of chitosan modified cnts (cs-cnts) composites to prepare carbon nanotubes hydrogels (cnts-gel). the products, named cs-mwcnts, were characterized by scanning electron microscope (sem) and fourier transform infrared (ftir) spectroscopy. swelling properties and effect of ph on controlled release performanc...