Introduction . Fibrolamellar hepatocellular carcinoma (FlC) is a rare subtype of (HCC). Drug antitumor treatment FlC has not been studied sufficiently due to the rarity pathology and requires further research choose an effective treatment. Aim The choice drug in patients with fibrolamellar liver carcinoma. Materials methods retrospective study included 31 who received therapy at N.N. Blokhin Na...

the marked shift in the patterns of drug use in iran, from opium smoking to injecting drug use, has led to serious health-related outcomes. this study was designed to explore characteristics of people who inject drugs (pwid) in tehran, iran. nine hundred and four pwid were recruited from treatment and harm reduction facilities, as well as drug user hangouts in public areas in tehran. participan...

Acute myocardial infarction (AMI) is one of the main leading causes of mortality and morbidity. Despite the progress in the treatment of AMI, streptokinase is still being used in many countries. Because of the critical condition of patients with AMI and complications of streptokinase therapy, this study was performed to evaluate the pattern of adverse drug reaction (ADRs) induced by streptokina...

introduction : drug addiction and drug dependency are major problem in the “mental”,”social”, and “health-care” fields. it decreases occupational performance and educational abilities in different social groups, and may lead to miscellaneous crimes. different methods are recommended for drug addiction treatments. detoxification is the first step however it would not be successful without follow...

Increasing tendency to drug use is a major social problem, Treatment attempts, regardless of the motivation, are not complete. The study aimed to investigate the relationship between treatment motivation, substance use, craving, withdrawal symptoms and health locus of control in addicted patients. Research population this study included all male and female patients referring to the addiction tr...

introduction: addiction is a habit or behavior that is often hard to quit. it is estimated that 190 million persons are substance users around the world. substance abuse creates tolerance after a while. shortly after taking the drug, a person will not enjoy as the beginning of its use that is why the amount of substance used is gradually increased. the purpose of this study was to find the reas...

Background: The aim of the conservative treatment is the regression of the hyperplastic to normal endometrium. Conservative treatment of endometrial hyperplasia is based on the administration of agents with either antioestrogenic action or direct anti-proliferative effect on the endometrium. Progestagens have been used widely in the treatment of endometrial hyperplasias. Materials and Methods: ...

Aim: Diabetes treatment and follow-up is more difficult sensitive in the elderly. Sodium glucose co-transporter type 2 (SGLT2) inhibitors are newly developed antidiabetic agents. In geriatric age group, use of SGLT2 may be riskier terms side effects. We planned to evaluate effect tolerability using patients. Material Methods: Patients over 65 years with a diagnosis DM who were started on empagl...

BACKGROUND Medications are frequently prescribed outside their regulatory approval (off-label) by physicians particularly where appropriate therapies are not available. However, the risk/benefit ratio of drugs in off-label use needs to be critically appraised because it may differ from approved on-label usage. Therefore, an extensive exploration of current evidence on clinical data is well-advi...