Background The receptor tyrosine kinase AXL is aberrantly expressed in many cancer types and associated with epithelial-to-mesenchymal transition (EMT), poor prognosis, therapy resistance. To better understand the expression of this gene across specific disease subtypes, correlated pathways, how certain therapies potentially modulate expression, we investigated real-world clinical molecular dat...

{ In this paper, we investigate from several angles the adaptive quantization problem based on quantized causal past data (cf. Ortega and Vetterli, 1994). First, when stationarity and ergodicity are assumed, it is shown that the marginal density can be estimated consistently based on quantized past data in the parametric case. Then, in the non-parametric ase, we analyze the piecewise linear app...

Many studies try to determine whether Ancient Greek is an OV or VO language. All of them, however, fail to conduct a research whose method is entirely clear. This paper presents the first attempt to quantify the number of verbs governing preverbal or postverbal accusative object nouns or pronouns in single or coordinate independent clauses in Homer’s Iliad and Odyssey, Herodotus’ Histories, and...

Haviv [European J. Combin., 81 (2019), pp. 84--97] has recently proved that some topological lower bounds on the chromatic number of graphs are also their orthogonality dimension ov...

Cholangiocarcinoma (CCA) caused by infection of the liver fluke Opisthorchis viverrini, (Ov) is the major public health problem in northeast Thailand. Following Ov infection the subsequent molecular changes can be associated by reactive oxygen species (ROS) induced chronic inflammation, advanced periductal fibrosis, and cholangiocarcinogenesis. Notably, resistance to an activation of cell death...

The eVects of dopamine on developmental stuttering was studied in a 44 year old man with developmental stuttering and Parkinson’s disease during three levodopa “on” periods and three “oV” periods. When compared with the “oV” periods, during the “on”’ periods he demonstrated an increase of speech dysfluencies. These findings lend support to the dopamine hypothesis of developmental stuttering. (J...

Gas-chromatographic retention indices are given, in terms of methylene units, for 155 metabolically important compounds (mostly organic acids) as trimethylsilyl derivatives on 10% OV-1 and 10% OV-17 columns. Comprehensive references on metabolic diseases that can be diagnosed by detection of these metabolites are cross-indexed to facilitate the use of the methylene-unit list. With the data pres...

Oxygen vacancies-enriched black TiO2 is one promising support for enhancing hydrogen evolution reaction (HER). Herein, oxygen vacancies enriched supported sub-nanometer Pt clusters (Pt/TiO2-OV) with metal interactions designed through solvent-free microwave and following low-temperature electroless approach the first time. High-temperature strong reductants are not required then can avoid aggre...

We have analyzed the secondary structure in the region surrounding the initiation codons of both cellular and synthetic versions of ovalbumin mRNA. RNase V1 cleavage sites and structure-dependent, chemically modified bases in cellular ovalbumin mRNA were determined by reverse transcription of hen poly A(+) RNA using ovalbumin-specific, synthetic DNA primers. These results indicate an extensive ...