Several studies have reported that pancreatic ductal preservation greatly improved the islet yield and function after cold storage. However, these studies were devoid of appropriate controls, such as vascular perfusion, which is routinely performed to preserve organs in the clinical setting. In this study, we created a vascular perfusion model using inbred rats, and investigated the effect of d...

pulmonary arteriovenous malformations are rare clinical entities thai are associated with right to left shunts, and are often clinically presented by the triad of dyspnea, cyanosis, and digital clubbing. currently, transcatheter embolization of fistula is gaining increasing popularity as the superior therapeutic option. in certain situations, however, surgery is preferred. two cases of direct p...

background: arteriovenous malformations are one of the most common vascular disorders of the colon. vascular disorders present as painless, high-volume rectal bleeding. case presentation: this study elucidates two rare cases of vascular disorders that are diagnosed as angiodysplasia of the left colon and cavernous hemangioma of the colon and rectum.  the chief complaint in two patients was rect...

Seven neonates with arteriovenous malformation of the vein of Galen are described. Six presented with cyanotic heart failure. Two cases had antenatal cerebral infarction, five periventricular leukomalacia, and three recent haemorrhagic infarction. Cerebral damage due to the malformation suggests that surgical correction of the arteriovenous malformation offers little to neonates, though after t...

W e demonstrate a new hyperpigmentation on the tongue of a 68-year-old female patient who was diagnosed with stage IIA infiltrating ductal carcinoma of the left breast who underwent modified radical mastectomy followed by a triple chemotherapy regimen which consisted of doxorubicin, docetaxel, and cyclophosphamide. The patient developed the tongue hyperpigmentation a few weeks after the initiat...

A three generation family with Rieger eye malformation sequence is described. No other abnormalities were present apart from the eye malformation. Linkage to EGF and D4S193 localised in 4q25 was excluded and this indicates that Rieger eye malformation is genetically different from typical Rieger syndrome with teeth and umbilical anomalies.

The complete or partial spontaneous disappearance of a cerebral arteriovenous malformation is rare. Spontaneous thrombosis in large arteriovenous malformations has been reported in only two cases. We report the case of a large arteriovenous malformation in a 17-year-old man, that thrombosed spontaneously after minor surgical manipulation and review the literature and some possible mechanisms fo...

Split-hand/split-foot malformation is a rare limb malformation with median clefts of the hands and feet and aplasia/hypoplasia of the phalanges, metacarpals and metatarsals. When present as an isolated anomaly, it is usually inherited as an autosomal dominant form. We report a case of autosomal recessive inheritance and discuss the antenatal diagnosis, genetic counseling and treatment for the m...

Abstract Ebstein’s anomaly is a rare congenital malformation of the right ventricle and tricuspid valve which characterized by several features that can exhibit an infinite spectrum malformation. The abnormalities include: i) adherence leaflets to underlying myocardium (failure delamination); ii) anterior apical rotational displacement functional annulus (septal > posterior leaflet); iii) di...

background and objective: nonsteroidal anti-inflammatory agents are the treatment of choice for ductal closure in premature newborn. this study evaluates early and late outcome, as well as the effectiveness of oral ibuprofen in the treatment of patent ductus arteriosus (pda) in premature infants. methods: in this clinical trial, all preterm infants below 37 weeks, with documentation of pda were...