Histopathological studies were made on 9 necropsy specimens of ductus arteriosus with hypoplastic left heart syndrome and I with rubella syndrome. A control group of 40 normal specimens were also studied. In the 17th week of gestation, ductus arteriosus was composed of few elastic fibers, a thick continuous internal elastic lamina and a wide hypocellular area. In the 8th month of gestation, the...

BACKGROUND AND OBJECTIVES To assess the safety and efficacy of transcatheter closure of residual ductal flow after initial surgical ligation of the arterial duct. SUBJECTS AND METHODS Between June 2005 and December 2009, transcatheter occlusion of residual postsurgical ductus arteriosus was performed in six children. RESULTS The mean patient age was 10±5.5 years; mean post-procedural time s...

A 14-month-old girl was evaluated for noisy breathing and swallowing. An upper gastrointestinal barium swallow study showed a filling defect of the esophagus at the level of the aortic arch suggestive of a vascular ring (Figures 1 and 2). A chest computed tomography angiogram with 3-dimensional reconstruction (1-mm sections; Movies I and II in the onlineonly Data Supplement) showed a vascular r...

Aneurysm of the ductus arteriosus is a very rare congenital lesion in adults that can be associated with thromboembolism, rupture, and death. Its detection in a silent clinical phase is very important for planning appropriate treatment and avoiding potentially fatal complications. We report a case of a patent ductus arteriosus aneurysm of very large size (65.5 mm) that was incidentally discover...

More than three decades have passed since the introduction of transcatheter devices for closure of patent ductus arteriosus, and many occluders have been made available since then. The ideal requirements of any procedure are a user-friendly technique, optimum success rate, no residual anomaly, minimal morbidity/mortality, and comparability or superiority to the existing conventional modality of...

We report our experience with stenting of the ductus arteriosus in three neonates. Two patients had pulmonary atresia with an intact interventricular septum and one had critical pulmonary stenosis. Radiofrequency ablation was used to open the atretic pulmonary valve in two patients. In all three patients implanting a stent avoided the need for surgical creation of a Blalock-Taussig shunt. In tw...

Ibuprofen is used for the closure of ductus arteriosus either intravenously or enterally. Although intraventricular hemorrhage, necrotizing enterocolitis, bronchopulmonary dysplasia, transient renal failure, oliguria, hyponatremia and thrombocytopenia are reported complications during or after ibuprofen treatment, gastrointestinal bleeding, to our knowledge, has not been reported previously. We...

An adult with a large patent ductus arteriosus may present with fatigue, dyspnea or palpitations or in rare presentation with endocarditis. The case illustrated unique role of vegetation of endocarditis in hemolytic anemia in adult with patent ductus arteriosus (PDA). Despite treatment of endocarditis with complete course of appropriate antibiotic therapy and normality of C- reactive protein, e...

Fig. 2. (A) Multi-slice computed tomography images showed extravasation of the contrast media into themediastinumwith surrounding hematoma, not only in the mediastinum but also into the left lung tissue. (B) Three dimensional volume-rendering images from the computed tomography scan clearly demonstrated leakage of the contrast media at the bifurcation of the ductus arteriosus and lesser curvatu...