Helicobacter pylori status, gastric histology, and 24 hour acidity were studied in 35 gastritis patients, 21 duodenal ulcer patients, and 14 subjects with normal gastric mucosa. H pylori was identified in 21 of 35 patients with chronic active gastritis and in 19 of 21 duodenal ulcer patients, but in none of those with normal gastric mucosa. Mean scores of activity of gastritis were similar in H...

This paper shows that in Nigeria as in England there is an excess of blood group O in patients with duodenal ulcer.

Hereditary predisposition is one of the aetiopathogenetic factors in development gastric ulcer and duodenal ulcer. The analysis literature materials allows us to identify a number candidate genes that play role formation peptic ulcer: PSCA, ABO, IL1β, IL1RN, TNFα, HSP70-1, GSR, TLR4, TLR2, TLR9, MMP-1, MMP-3, MMP- 9, TIMP-3, PGC, MIF, MPO, COX-1. Considering most studies were carried out abroad...

BACKGROUND Gastro-duodenal perforations are common and may complicate peptic ulcer disease. Management is often by surgical closure. OBJECTIVE To determine the patterns of presentation and mode of management of duodenal ulcer perforations. METHODS Retrospective review of patients with duodenal ulcer perforations seen at the Obafemi Awolowo University Teaching Hospital between June 2001 and ...

In a prospective controlled trial, histamine concentrations in human gastric mucosa were determined fluorometrically in 23 patients 6-11 months after selective gastric vagotomy with drainage and in patients who had undergone other types of operation for duodenal ulcer. The study was in twoparts: part I , a synchronous investigation of mucosal histamine concentrations in patients who had undergo...

background peptic ulcer disease is a multifactorial health problem affecting almost all populations worldwide. large scale population-based studies are crucial to understanding its scope and specifications in various nations. we aimed to explore environmental risk factors of peptic ulcer disease in the first population based study in ardabil, northwest iran. methods this study was a part of a l...

Peptic ulcer embraces both gastric and duodenal ulcers and has been a major threat to the world’s population over the past two centuries, with a high morbidity and substantial mortality. Discovery of gastric mucosa infection with Helicobacter pylori (H. pylori) and its association with chronic antral gastritis and peptic ulcer revolutionized the treatment of ulcer illness. H. pylori are causall...

Between January 1968 and December 1977 a total of 230 patients with a perforated duodenal ulcer underwent emergency operation in the Royal Victoria Hospital. Simple suture closure of the perforation was carried out in 205, and in the remaining 25 a definitive ulcer procedure was performed in addition. Four patients died following operation, a mortality rate of 1.7%.During a mean follow-up perio...