Renal Cell Carcinoma (RCC) is the most prominent kidney cancer derived from renal tubules and accounts for roughly 85% of all malignant kidney cancer. Every year, over 60,000 new cases are registered, and about 14,000 people die from RCC. The incidence of this has been increasing significantly in the U.S. and other countries. An increased understanding of molecular biology and the genomics of R...

One of the most remarkable developments in marketing is the amount of interest shown in market segmentation and an important strategy in modern marketing as it provides an insight into the target pricing and advertising policies for technological products. Developers of technological products keep introducing successive generations of product based on latest technology, either to continue to be...

An extensive body of literature argues for the benefits of planned obsolescence, the strategy of designing products with low durability to induce repeat purchases from the consumers. Yet, some firms avoid planned obsolescence and instead offer products with high durability. In this paper, we offer a demand-side rationale for a high-durability product design strategy: exclusivity-seeking consume...

This paper aims to lay a theoretical foundation on how individuals value durable products. In this paper we emphasize ownership and analyze why customers want to own products and the value they give to ownership. Specifically, we argue that the ownership of a product represents a bundle of options. At any given point in time, the owner of a product has the option to choose whether she wants to ...

Plastics are increasingly a preferred material choice in designing and developing complex, consumer products, such as automobiles, because they are mouldable, lightweight, and are often perceived to be highly recyclable materials. However, actually recycling the heterogeneous plastics used in such durable items is challenging, and presents very different scenarios to how simple products, such a...

Historical renders are exposed to several degradation processes that can lead to a wide range of anomalies, such as scaling, detachments and pulverization. Among the common anomalies, the loss of cohesion and adhesion are usually identified as the most difficult to repair; these anomalies still need to be deeply studied to reach compatible, durable and sustainable conservation treatments. The r...

Abrasion and corrosion resistant steel has attracted considerable interest for industrial application as a means of minimising the costs associated with product/component failures and/or short replacement cycles. These classes of steels contain alloying elements that increase their resistance to abrasion and corrosion. Their benefits, however, currently come at a potentially prohibitive cost; s...

All activities should aim to eliminate genotoxic impurities and/or protect the API against degradation. There is a necessity to monitor impurities from all classification groups, hence ivabradine forced degradation studies were performed. Ivabradine was proved to be quite durable active substance, but still new and with insufficient stability data. Increased temperature, acid, base, oxidation r...

<p style='text-indent:20px;'>In this paper, we discuss if and which pricing policies by a manufacturer who sells its products online motivate retailer as an independent part to enter the market provide selling leasing options through brick store. Moreover, impact of shopping preferences brand image on end-user behavior is examined, different consumption patterns are considered. For purpos...