Evidence of a lower urinary tract dysfunctional epithelium has been detected in women and men with interstitial cystitis and other complexes of lower urinary tract symptoms. Lower urinary tract dysfunctional epithelium can affect the bladder, the urethra, the labia or vaginal introitus in women, and the prostatic ducts and urethra in men. Because an individual with lower urinary tract dysfuncti...

Reversing the dysfunctional T cell state that arises in cancer and chronic viral infections is the focus of therapeutic interventions; however, current therapies are effective in only some patients and some tumor types. To gain a deeper molecular understanding of the dysfunctional T cell state, we analyzed population and single-cell RNA profiles of CD8(+) tumor-infiltrating lymphocytes (TILs) a...

nent feature of our modern medical care system. Over the last 40 years the ‘medical team’ or ‘firm’ has changed in many ways resulting in a way of working which can be deeply satisfying for the team members and beneficial to patients they care for. However, if the team does not function well as a unit the reverse can apply, with much dissatisfaction among staff, and substandard treatment of pat...

The authors present a specific aspect of the modifications of the endometrium in dysfunctional uterine hemorrhages that is the behavior of the endometrial glands. These glands are studied from a immunohistochemical point of view, regarding both the normal endometrium (inclusively at the age of two years) and the endometrium in dysfunctional uterine hemorrhages. The antigens used were VGEF and P...

Everyday teaching requires teachers to deal with a variety of pedagogical issues, such as classroom disruptions. Against the background on-going calls for an evidence-informed practice, should ground their decisions not only on subjective theories or experience-based knowledge but also educational and empirical findings. However, research suggests that pre- in-service rather refer experiential ...

The characteristics associated with COVID-19-related dysfunctional grief suggest that we are most likely facing a “dysfunctional pandemic” due to COVID-19. Thus this preliminary study reports frequencies of in ten Latin American countries varied between 7.3% Brazil and 14.6% El Salvador. This highlights greater need for work together improve the accessibility treatment grief.

Objective: To quantify regional left ventricular (LV) function and contractile reserve in Q wave and non-Q wave regions in patients with previous myocardial infarction. Design: An observational study. Setting: Tertiary care centre. Patients: 81 patients with previous myocardial infarction and depressed LV function. Interventions: All patients underwent surface ECG at rest and pulsed wave tissue...