BACKGROUND Unlike major depression, the psychosocial impact of dysthymia has received far less research attention. This study attempted to assess the psychosocial consequences of dysthymia. METHODS The sample consisted of 30 married patients with DSM-IV dysthymic disorder and a matched control group of 30 married patients with recurrent major depressive disorder (RDD), diagnosed using structu...

OBJECTIVE In this study, we aimed to investigate the prevalence, association with sociodemographic characteristics, and comorbidity with other anxiety and depressive disorders of generalized anxiety disorder (GAD) among psychiatric outpatients. METHOD In the first phase of the study, outpatient psychiatry clinic physician interviewed with consecutive 950 patients who applied to psychiatry out...

self-reported symptoms suggestive of ADHD. The diagnosis of adult ADHD can be challenging because these self-reported symptoms are not objectively verifiable. The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), emphasizes both inattention and impulsivity/hyperactivity, but these symptoms may be subtle and difficult to elicit in adults. Symptoms are usually longst...

BACKGROUND Data on the duration of major depressive episodes (MDE) in the general population are sparse. AIMS To assess the duration of MDE and its clinical and socio-demographic determinants in a study group drawn from the general population with newly originated episodes of major depression. METHOD The Netherlands Mental Health Survey and Incidence Study is a prospective epidemiological s...

Background: Post partum psychosis is a mood disorder which starts 2 or 3 weeks after delivery. In acute form, the symptoms of this disorder are so obvious that the sick mother doesn’t want to take care of her child in some cases, she wants to hurt either the child or herself or both (the child & the mother). It seems that there are some psychosocial factors that cause this problem to occur. Ma...

These practice guidelines for the biological treatment of unipolar depressive disorders were developed by an international Task Force of the World Federation of Societies of Biological Psychiatry (WFSBP). The goal for developing these guidelines was to systematically review all available evidence pertaining to the treatment of the complete spectrum of unipolar depressive disorders, and to produ...

OBJECTIVE To examine prospectively the course of major depressive disorder (MDD) and to test for the moderating effects of personality disorder (PD) comorbidity on relapse after remission from an episode of MDD. METHOD Participants were 303 patients (196 women and 107 men) with current DSM-IV-diagnosed MDD at baseline enrollment in the Collaborative Longitudinal Personality Disorders Study. M...

BACKGROUND Social anxiety disorder (SAD) (also known as "social phobia") is frequently comorbid with major depression, and in such cases, almost always precedes it. This has led to interest in SAD as a possible modifier of the risk and/or course of mood disorders. METHODS Data come from a prospective, longitudinal epidemiologic study of adolescents and young adults (aged 14-24 years) in Munic...

Epidemiological evidence supports comorbidity of generalized anxiety disorder (GAD) and major depressive disorder (MDD) or dysthymia, and its association with significant disability. As pregabalin, a new alpha(2)-delta anxiolytic treatment for GAD, unlike most other licensed treatments for GAD has not undergone investigation in patients with MDD, we examined its efficacy in depressive symptoms ...