نتایج جستجو برای: early virologic response

تعداد نتایج: 1595197  

2018

Successful hepatitis C treatment results in sustained virologic response (SVR), which is tantamount to virologic cure and, as such, is expected to benefit nearly all chronically infected persons. When the US Food and Drug Administration (FDA) approved the first interferon-sparing treatment for HCV infection, many patients who had previously been “warehoused” sought treatment. The infrastructure...

2018

Successful hepatitis C treatment results in sustained virologic response (SVR), which is tantamount to virologic cure and, as such, is expected to benefit nearly all chronically infected persons. When the US Food and Drug Administration (FDA) approved the first interferon-sparing treatment for HCV infection, many patients who had previously been “warehoused” sought treatment. The infrastructure...

Journal: :Journal of hepatology 2009
Alessandro Grasso Federica Malfatti Pasqualina De Leo Hugo Martines Paolo Fabris Federica Toscanini Marco Anselmo Giorgio Menardo

BACKGROUND/AIMS The rapid decline in hepatitis C virus RNA is crucial for determining the outcome of therapy in patients with genotype 1 chronic hepatitis C. However, the variables influencing the early phase of viral decay are still largely unexplored. We aimed to assess which pre-treatment variable may predict rapid virologic response (RVR) and sustained virologic response (SVR). METHODS We...

2018

Successful hepatitis C treatment results in sustained virologic response (SVR), which is tantamount to virologic cure and, as such, is expected to benefit nearly all chronically infected persons. When the US Food and Drug Administration (FDA) approved the first interferon-sparing treatment for HCV infection, many patients who had previously been “warehoused” sought treatment. The infrastructure...

Journal: :Gastroenterology 2010
Theodora E M S de Vries-Sluijs Jurriën G P Reijnders Bettina E Hansen Hans L Zaaijer Jan M Prins Suzan D Pas Martin Schutten Andy I M Hoepelman Clemens Richter Jan W Mulder Rob A de Man Harry L A Janssen Marchina E van der Ende

BACKGROUND & AIMS We investigated the long-term efficacy and renal safety of tenofovir disoproxil fumarate (TDF), administered to patients co-infected with human immunodeficiency virus and hepatitis B virus (HBV) as part of an antiretroviral therapy. METHODS We performed a multicenter, prospective cohort study of 102 patients co-infected with human immunodeficiency virus and HBV who were trea...

2011
Shiying Li Peng Hu Qin-Qin Zhang Ying-Hong Liu Huai-Dong Hu Da-Zhi Zhang Hong Ren

BACKGROUND Hepatitis C is a global health problem and represents a major cause of liver disease and socioeconomic burden. Effective antiviral therapy may prevent these complications, but the current treatment for patients with chronic hepatitis C virus (HCV) infection does not produce sustained virologic response. Therefore, identification of the determinants of response to treatment is a high ...

Journal: :hepatitis monthly 0
bruno cacopardo department of clinical and molecular biomedicine, division of infectious diseases, university of catania, italy +39-0957598443, [email protected]; department of clinical and molecular biomedicine, division of infectious diseases, university of catania, italy +39-0957598443, [email protected] marilia rita pinzone department of clinical and molecular biomedicine, division of infectious diseases, university of catania, italy +39-0957598443, [email protected] filippo palermo department of clinical and molecular biomedicine, division of infectious diseases university of catania, italy giuseppe nunnari department of clinical and molecular biomedicine, division of infectious diseases, university of catania, italy +39-0957598443, [email protected]; department of microbiology and immunology, jefferson medical college, thomas jefferson university, usa

background il-33 is a novel member of the il-1 family, which has been shown to play an important role in t helper 2 (th2)-associated immune responses. recent studies have suggested a possible role for il-33 in the pathogenesis of liver damage during acute and chronic hepatitis; furthermore, il-33 may be involved in the development and progression of liver fibrosis. objectives to evaluate serum ...

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