Three-dimensional (3D) echocardiography has a long history with the first 3D-reconstruction of 2D images described in 1974 by Dekker et al. With their approach, the patient was scanned with a transducer attached to a mechanical arm that fed quadrant data to a computer mainframe. However, equipment such as this was impractical and images were unsuitable for clinical use. Over the subsequent deca...

This thesis focuses on deformation tracking and diffeomorphic matching in 2D or 3D medical imaging. We have developed and implemented novel algorithmic approaches to track both the myocardial motion in 2D IntraCardiac Echocardiography images and the Mitral Valve deformation in 3D ultrasound images. We studied the myocardial deformation through the registration of IntraCardiac Echocardiography i...

Magnetic resonance imaging at a high field strength has potential benefits for the study of the heart in infants, which is when most congenital heart disease presents. Seventeen infants with various anatomical types of ventricular septal defect were studied by this technique. Good quality, high resolution, images were obtained in every case. There were no major practical problems. The morpholog...

Three-dimensional (3D) echocardiography has a long history with the first 3D-reconstruction of 2D images described in 1974 by Dekker et al. With their approach, the patient was scanned with a transducer attached to a mechanical arm that fed quadrant data to a computer mainframe. However, equipment such as this was impractical and images were unsuitable for clinical use. Over the subsequent deca...

Three-dimensional (3D) echocardiography has a long history with the first 3D-reconstruction of two-dimensional (2D) images in 1974. However, the equipment was impractical and images were unsuitable for clinical use. Over the subsequent decades, several researchers, primarily in biomedical engineering, worked on overcoming technical challenges to make the equipment smaller, yet capable of genera...

Dual-isotope myocardial SPECT in a female patient with idiopathic myocarditis showed completely inverse images in Tl-201 and I-123 MIBG SPECT. In the dual-isotope SPECT performed 13 days after her admission, Tl-201 SPECT images showed reduced accumulation in the apex and normal accumulation in the other regions, whereas the corresponding I-123 MIBG SPECT images showed normal findings in the ape...

Congenital quadricuspid aortic valve (QAV) is a rare cardiac anomaly. Several different anatomical variations of a quadricuspid aortic valve have been described. Aortic regurgitation is the predominant valvular dysfunction associated with QAV and patients tend to present in their 5(th) or 6(th) decade of life. This anomaly is rarely picked up by transthoracic echocardiogram (TTE). A comprehensi...