BACKGROUND AND OBJECTIVE This study aims to look at the pattern and incidence of skin diseases seen in Dermatology/Venereology clinic at the University of Benin Teaching Hospital, Benin City, Edo State, South-South Zone, Nigeria and compare it with other zones of Nigeria. MATERIALS AND METHODS This was a prospective study on pattern and incidence of skin diseases in new patients presenting at...

Prof. Carlo Crosti, Clinica Dermatologica, Ospedale San Paolo, Via A Di Rudini, 8, I-20142 Milano (Italy) Despite its frequency, pompholyx or dyshidrotic eczema presents many unresolved problems of aetiology, pathogenesis and therapy. As its invariable histopatholog-ical picture of spongiotic dermatitis indicates, pompholyx is a non-specific reaction somehow related to the particular anatomy of...

OBJECTIVES To investigate the incidence of skin prick test (SPT) positivity in patients with eczematous external otitis. METHODS Forty-six patients with eczematous external otitis and forty-four healthy volunteers were included in the study. All the patients were skin-tested by prick test. Reactions were assessed by the degree of redness and swelling and the size of the wheal produced. RESU...

BACKGROUND Recent studies have suggested that epidermal barrier dysfunction contributes to the development of atopic dermatitis (AD) and other allergic diseases. OBJECTIVE We performed a prospective, randomized controlled trial to investigate whether protecting the skin barrier with a moisturizer during the neonatal period prevents development of AD and allergic sensitization. METHODS An em...

A 55-year-old man presented with generalized eczema and nodules. Physical examination revealed eczematous skin lesions on the face, trunk and extremities, with localized lichenification (Fig. 1A). Poikilodermatous skin changes were observed in the anterior neck and upper chest (Fig. 1B). In addition, numerous whitish dermal nodules 0.5–2 cm in diameter were observed on the trunk and extremities...

BACKGROUND Most study concerning the prevalence and dermatological manifestations of the extrinsic and the intrinsic form of atopic dermatitis (AD) were performed in children and adult AD related to the early-onset AD extending to adult life. Adult-onset AD is a subgroup of AD. Apart from the typical eczematous flexural distribution pattern of AD, this group may also have nontypical morphology ...

Influence of a nematode immunomodulator and a nematode infection on two models of allergic disease Parasitic worms, like filariae, have the intriguing capacity to modulate immune responses directed against them, and therefore can persist up to years in a host. This immunomodulation does not only protect the parasite but was found to mediate a negative correlation between infections with parasit...

BACKGROUND Vitamin E (VE) is a potent antioxidant that can improve the immune macrophage-mediated response, decrease the production and/or release of prostaglandins in humans, and decrease the serum levels of immunoglobulin E (IgE) in atopic subjects. AIM To compare the effects of placebo (PL) and VE intake (400 IU/day) on subjective symptoms and serum IgE levels in 96 subjects with atopic de...

Objective: During the ongoing coronavirus disease-2019 (COVID-19) pandemic, overall number of patients presented to dermatology outpatient clinics has decreased. This study aims examine elderly during COVID-19 periodic variation in patients, and most common reasons for their presentation. Material Methods: retrospectively analyzed 448 presentations 381 aged ≥60 years between March 11 May 31, 20...