Case reports of neurogenic pulmonary edema (NPE) often indicate that the edema resolves quickly. Because plasma epinephrine concentration may be elevated in NPE, and epinephrine has been shown to increase the rate of alveolar liquid clearance (ALC), we determined if ALC was increased in a canine model of NPE produced by the intracisternal administration of veratrine. ALC was determined by insti...

BACKGROUND AND PURPOSE Late hypothermia (HYPO) reduces injury after collagenase-induced intracerebral hemorrhage (ICH), whereas early HYPO does not because it exacerbates the protracted bleeding that occurs in this model. We hypothesized that early HYPO would not increase bleeding after whole blood infusion and thus expected early HYPO to improve outcome through reducing secondary consequences ...

In a prospective study, 20 patients with arm lymphedema after breast cancer treatment underwent liposuction combined with Controlled Compression Therapy (CCT) or CCT alone. Indirect lymphoscintigraphy (ILS) was used to study lymph kinetics before and after intervention. Lymphoscintigrams from the contralateral, non-edematous arm were characterized by prompt transit of the radiotracer (99mTc-alb...

(Chest 1992; 101:258-60) P ulmonary edema may be anticipated in patients with cardiac failure and high central circulatory pressures as reflected in pulmonary artery wedge levels of 20 to 30 mm Hg,’ but does not occur at the same pressure levels with pencardial compression of the heart.2 Yet, in the systemic circulation, both rightsided cardiac failure and compressive pencardial disorders cause...

where Qf is the net transvascular fluid flow, K is the fluid filtration coefficient, P is the hydrostatic pressure in the microvascular* lumen (mv) and perimicrovascular* interstitial fluid (pmv), respectively; a is a weighted plasma protein reflection coefficient which determines the "effective" transvascular protein osmotic pressure difference; and II is the protein osmotic pressure in the pl...

BACKGROUND Treatment for breast cancer has increased patient survivorship exponentially over the past few decades. With increased survivorship, more women are living with the longstanding effects of breast cancer treatment, such as lymphedema. Patients, health care providers, and payers depend on practical and efficient clinical measures to accurately diagnose and monitor disease progression or...

BACKGROUND AND PURPOSE Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis and a strong vascular permeability factor. VEGF is known to open the blood-brain barrier (BBB) and induce cerebral edema. Experimental studies of VEGF antagonism have shown it reduces cerebral edema after ischemia, indicating its potential for prevention of secondary brain damage. We examined th...

objective(s) opioid abuse is still remained a major mental health problem, a criminal legal issue and may cause ischemic brain changes including stroke and brain edema. in the present study, we investigated whether spontaneously withdrawal syndrome might affect stroke outcomes. materials and methods addiction was induced by progressive incremental doses of morphine over 7 days. behavioral signs...

OBJECTIVE This retrospective study investigated the efficacy and safety of bevacizumab treatment for refractory brain edema. METHODS Between March 2009 and December 2015, bevacizumab was used to treat 59 cases of brain metastatic patients with refractory brain edema. The median dose of bevacizumab was 4.68 mg/kg (range 2.8-6.52 mg/kg). The clinical-pathological data, the efficacy, and the sid...