Relapsing polychondritis is an inflammatory disease of connective tissue characterized by the destruction of hyaline and elastic cartilages . Although the etiology of this disease is unknown, the demonstration of anti-cartilage antibodies in the sera of patients with this disorder suggests an autoimmune mechanism (1, 2) . Recently, Foidart et al . (3) have reported an association between relaps...

Objective- To determine the effect of the transcutaneous electrical neural stimulation on healing of hip joint cartilage defect in rabbit.Design- Experimental in vivo study.Animals- 12 adult New Zealand rabbits were used.Procedures- Under effective the right femoral head was subluxated and the maximum accessible cartilage was denuded up to subchondral bone using dental bit in each rabbit. Then ...

introduction: to demonstrate surgical techniques and to compare the anatomical and functional outcomes between temporalis fascia and cartilage palisade grafting in type-i underlay tympanoplasty in patients with large/subtotal perforation.materials and methods:temporalis fascia and cartilage palisade grafting were conducted in group a and group b, respectively, each containing 30 patients with l...

background filler materials are gaining popularity in nonsurgical rhinoplasty the major advantages are the ability to camouflage the surface deformities, and also the soft and malleable consistency while the major drawback of the safe fillers such as hyaluronic acid is short durability. in this study, we evaluated the injectable cartilage shaving as an autologous filler material for correction ...

The repair of articular cartilage lesions in weight-bearing joints remains as a significant challenge due to the low regenerative capacity this tissue. Hydrogels are candidates they have similar properties extracellular matrix but unable meet mechanical and biological requirements for successful outcome. Here, we reinforce hyaluronic acid (HA) hydrogels with 13-93-lithium bioactive glass micro-...

INTRODUCTION Articular cartilage is a highly inhomogeneous soft tissue with composition, structure, and mechanical properties that vary with depth and region. Its primary constituents (water, collagen II fibrils, and aggrecan proteoglycans) define its functional role as a load-bearing structure. An understanding of local structure-properties relationships in cartilage can help in identifying th...

articular cartilage, the load-bearing tissue of the joint, has limited repair and regeneration ability. the scarcity of treatment modalities for large chondral defects has motivated researchers to engineer cartilage tissue constructs that can meet the functional demands of this tissue in vivo. cartilage tissue engineering requires 3 components: cells, scaffold, and environment. owning to their ...

osteoarthritis is the most common joint disease.the main pathologic manifestation of disease is local destruction of cartilage in diarthrodial joint. new bone formation in marginal surface of the joint is a sign progressive disease. many systemic and local factors are introduced in initiate and progression of osteoarthritis include: age, sex, weight, race, genetic background, bone densitometry,...

background: since the treatments of long tracheal leisions are associated with some limitations, tissue enginered trachea is considered as an alternative option. this study aimed at preparing a composite scaffold, based on natural and synthetic materials for tracheal tissue engineering. methods: nine chitosan silk-based scaffolds were fabricated using three freezing rates (0.5, 1, and 2°c/min) ...