Design and fabrication of electrodes is key in the development of electrochemical sensors with superior electrochemical performances. Herein, an enzymeless electrochemical sensor is developed for detection of hydrogen peroxide based on the use of highly ordered polyoxometalate (POM)-doped polyaniline (PANI) nanopillar films. The electrodeposition technique enables the entrapment of POMs into PA...

Parabens are the antimicrobial molecules largely used in cosmetic products as a preservative agent. Among them, the methylparaben (MP) is the most frequently used ingredient in cosmetic preparations. Nevertheless, their potential dangers led to the development of sensible and reliable methods for their determination in environmental samples. Firstly, a sensitive and selective molecular imprinte...

Due to the nearly identical phenotypes and chemical constituents, it is often very challenging to accurately differentiate diverse species of a Chinese herbal genus. Although technologies including DNA barcoding have been introduced to help address this problem, they are generally time-consuming and require expensive sequencing. Herein, we present a simple sequencing-free electrochemical biosen...

We report a rapid, ultrasensitive, immobilization-free and signal-on electrochemical DNA biosensor with excellent discrimination ability for single-nucleotide polymorphisms. It achieves recognition signal generation by the specific cleavage function of exonuclease III and the diffusion different between oligonucleotides and mononucleotides towards a negatively charged ITO electrode surface. Mea...

A novel nanocomposite consisting of MoS 2 and AuNPs was prepared by a simple self-reduction method without reductant at room temperature. The as-prepared @AuNP nanocomposites were further used to construct an electrochemical glucose biosensor.

An amperometric biosensor for chlorphenvinphos (organophosphorus pesticide) based on carbon nanotube paste and acetylcholinesterase enzyme (CNTs-AChE biosensor) is described herein. This CNTs-AChE biosensor was characterized by scanning electron microscopy (SEM) and electrochemical impedance spectroscopy (EIS). The SEM result shows the presence of CNTs and small lumps, due to the enzyme AChE, w...

Nowaday, the construction of new electrochemical biosensors with improved bioanalytical performance and robustness is directly linked to the development of novel strategies for tailormade design of electrode surfaces. Such strategies should provide electrical interfaces with nanoor microsized tree-dimensional topology that allow the successful and stable immobilisation of the biomolecules witho...

The aim of this work is to present the experimental results in form an algorithm for analyzing modification screen printed electrodes, including possibility its regeneration irreversibly oxidizing biologically active compounds (drugs, DNA and proteins). A protocol was developed quantitative analysis study mechanism drug-DNA interaction by differential pulse voltammetry, following parameters: co...