We report a strategy for the reagentless transduction of DNA hybridization into a readily detectable electrochemical signal by means of a conformational change analogous to the optical molecular beacon approach. The strategy involves an electroactive, ferrocene-tagged DNA stem-loop structure that self-assembles onto a gold electrode by means of facile gold-thiol chemistry. Hybridization induces...

l-Glutamate is one of the most important neurotransmitters in the mammalian central nervous system, playing a vital role in many physiological processes and implicated in several neurological disorders, for which monitoring of dynamic levels of extracellular glutamate in the living brain tissues may contribute to medical understanding and treatments. Electrochemical sensing of glutamate has bee...

PANI-Ag-Fe nanocomposite thin films based electrochemical E. coli sensor was developed with thermal annealing. PANI-Ag-Fe nanocomposite thin films were prepared by oxidative polymerization of aniline and the reduction process of Ag-Fe bimetallic compound with the presence of nitric acid and PVA. The films were deposited on glass substrate using spin-coating technique before they were annealed a...

A sensor is defined as a device which detects a variable quantity, usually a non-electric stimulus and converts it into electrical signals that are recorded. Measurement performances are defined by the sensitivity, selectivity, accuracy and stability characteristics of the sensor. Because of their high degree of selectivity and sensitivity, electrochemical sensors represent a very promising ana...

Micro-nano structured Cu-Co was in situ fabricated on the surface of a gold electrode via electrochemical reduction of CuCl2 and Co(NO3)2. It is shown that the shape of the particles can be controlled by variation of deposition current, deposition time, pH value and the ratio of Cu(II) and Co(II) ions. If prepared under current of -200 μA in 0.1 M, pH 4.0 acetate buffer solution, the film posse...

An esterified pillar[5]arene has been incorporated into a PVC electrochemical membrane. The resulting pH-responsive sensor functions in the range of pH 1 to 4 in a non-linear manner.

The recent modernization of the livestock industry lags behind the scale of the livestock industry, particularly in indoor environmental monitoring. In particular, the H₂S gas concentration in chicken coops affects the growth and reproductive capacity of the chickens and threatens their health. Therefore, the research and development of a low-cost, environmentally friendly sensor that can achie...

An electrochemical mass sensor for clinically relevant detection of insulin in human serum conjugated to magnetic nanoparticles and captured onto antibody immobilized gold coated quartz resonators is reported for the first time.

We report a fully covalent, dual-signalling electrochemical DNA sensor that exploits competitive binding and target hybridization-induced change in probe flexibility for simple and robust detection of target DNA.

The ability of copper ions to affect the charge-transfer resistance of self-assembled monolayers (SAMs) of a tris-(2-pyridylmethyl)amine-based ligand on to gold electrodes is used to create a novel, sensitive and selective electrochemical cyanide sensor.