Discrete radiofrequency lesion at the atrial insertion site of the tendon of Todaro in the perfused rabbit preparation lengthens A-H interval, mimicking fast pathway input ablation. This study attempts to define the cellular electrophysiology of the ablation region prior to and after the elimination of fast AV node conduction. In six superfused rabbit AV node preparations, the cellular electrop...

UNLABELLED In recent years there has been much development of the fundamental ideas underlying mathematical model curation in regard to models of biology. While much has been achieved in the realms of systems biology and bioinformatics, little progress has been made in relation to cellular electrophysiology modeling. The primary reason for slow progress in this field is the lack of a consistent...

Cherry EM, Fenton FH. A tale of two dogs: analyzing two models of canine ventricular electrophysiology. Am J Physiol Heart Circ Physiol 292: H43–H55, 2007. First published September 22, 2006; doi:10.1152/ajpheart.00955.2006.—The extensive development of detailed mathematical models of cardiac myocyte electrophysiology in recent years has led to a proliferation of models, including many that mod...