نتایج جستجو برای: electroshock
تعداد نتایج: 623 فیلتر نتایج به سال:
The ATP-gated P2X7 receptor (P2X7R) is a non-selective cation channel which senses high extracellular ATP concentrations and has been suggested as a target for the treatment of neuroinflammation and neurodegenerative diseases. The use of P2X7R antagonists may therefore be a viable approach for treating CNS pathologies, including epileptic disorders. Recent studies showed anticonvulsant potentia...
Correlation between levels of anticonvulsants in the brain and maximal electroshock seizures in mice
Epilepsy and other seizure disorders are not adequately managed with currently available drugs. We recently synthesized a series of dibromophenyl enaminones and demonstrated that AK6 and E249 were equipotent to previous analogs but more efficacious in suppressing neuronal excitation. Here we examined the actions of these lead compounds on in vitro and in vivo seizure models. In vitro seizures w...
Objectives: To study the anti-convulsant potential of leaves of Psidium guajava Linn. in MES and PTZ induced convulsion in experimental animals. Materials and methods: The anticonvulsant potential of the ethanolic extracts of Psidium guajava Linn. (EEPG) were tested in the mice model of Maximal electroshock (MES) and Pentylenetetrazole (PTZ). In the MES model, seizures were induced by deliverin...
I. Anesthesia. XXXVII. The Anesthetic Action of Isopropyl Vinyl Ether. John C. Krantz, Jr., C. Jelleff Carr, Go Lu and Mary Jane Fassel 1 II. Synthetic Curare-Like Agents Which are Reversible by Tensilon. Lowell 0. Randall 7 III. The Conversion of Decamethonium-Like Agents to Tensilon-Reversible Agents by Aromatic Substituents. Lowell 0. Randall 16 IV. Effect of Adrenocortical Steroids and Adre...
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