The essence of tissue engineering is the fabrication of autologous cells or induced stem cells in naturally derived or synthetic scaffolds to form specific tissues. Polymer is thought as an appealing source of cell-seeded scaffold owing to the diversity of its physicochemical property and can be electrospun into nano-size to mimic natural structure. Poly (L-lactic acid) (PLLA) and poly (ε-capro...

Article history: Received on: 28/01/2016 Revised on: 17/03/2016 Accepted on: 18/05/2016 Available online: 28/07/2016 Herein we prepare antibacterial composite from carboxymethylchitosan (CMCS) nanofibers and silver nanoparticles (AgNPs) by using poly (vinyl alcohol) (PVA) as reducing, capping and fiber aiding material and investigated to be used in biomedical applications. The AgNPs has spheric...

The purpose of this study was to achieve a sustained release of hydrophilic l-ascorbic acid 2-phosphate magnesium (ASP) from electrospun polycaprolactone (PCL) scaffolds, so as to promote the osteogenic differentiation of stem cells for bone tissue engineering (TE). ASP was loaded and electrospun together with PCL via three electrospinning techniques, i.e., coaxial, emulsion, and blend electros...

Controlling the thickness of an electrospun nanofibrous scaffold by altering its pore size has been shown to regulate cell behaviors such as cell infiltration into a three-dimensional (3D) scaffold. This is of great importance when manufacturing tissue-engineering scaffolds using an electrospinning process. In this study, we report the development of a novel process whereby additional aluminum ...

Introduction: Rupture of the anterior cruciate ligament (ACL) is one of most common ligament injuries of the knee. Because of limitations associated with the use of autografts and allografts, as well as advances in regenerative medicine, there is an increasing interest in developing a tissue engineered substitute for biologic ACL grafts. Our group has developed an electrospun biodegradable poly...

Replicating the nanostructured components of extracellular matrix is a target for dermal tissue engineering and regenerative medicine. Electrospinning Bombyx mori silk fibroin (BMSF) allows the production of nano- to microscale fibrous scaffolds. For BMSF electrospun scaffolds to be successful, understanding and optimizing the cellular response to material morphology is essential. Primary human...

In this study, we report on electrospinning of functional polystyrene (PS) fibers containing cyclodextrinmenthol inclusion complexes (CD-menthol-ICs). Our goal is to develop functional electrospun fibers containing fragrances/flavors with enhanced durability and stability assisted by cyclodextrin inclusion complexation. We have used menthol as a model fragrance/flavor material and CD-menthol-IC...

Electrospun nanofibrous membranes (ENMs) are considered as a state of the art in water filtration technology mainly owing to their high interconnected porosity and tunable pore size assumed to offer a very high permeability also selectivity. However, the extremely high surface area makes the ENMs prone to mechanical breakdown and lack of wettability lowering the filtration efficiency. Hence, an...

Antimicrobial delivery has been advocated for guided tissue regeneration (GTR) or guided bone regeneration (GBR) therapies involving patients with aggressive or unresolved periodontitis/peri-implantitis. Electrospun chitosan membranes demonstrate several advantages over traditional GTR barrier membranes because they stimulate healing, mimic the topology of the extracellular matrix, and allow fo...

Polystyrene (PS) dissolved in a mixture of N, N-dimethylformamide (DMF) and/or tetrahydrofuran (THF) was electrospun to prepare fibers with sub-micron diameters. The effects of electrospinning parameters, including solvent combinations, polymer concentrations, applied voltage on fiber morphology, as well as tensile and hydrophobic properties of the fiber mats were investigated. Scanning electro...