Thienopyrimidine-based bisphosphonates were identified as a new class of nitrogen-containing bisphosphonate (N-BP) inhibitors of the human farnesyl pyrophosphate synthase (hFPPS). Analogs were prepared via cyclization of 2-(1-(trimethylsilyl)ethylidene)malononitrile to 2-amino-4-(trimethylsilyl)thiophene-3-carbonitrile in the presence of elemental sulfur. Direct ipso-iododesilylation of this in...

Cyclic voltammogram of ionic liquid and metallic-salts in ionic liquids were recorded. Cu/Sn/Zn stacked layers were electrodeposited and subsequently sulfurized in a tube furnace in elemental sulfur at 550oC. Thin films were characterized by X-ray diffraction, ICP-MS, and SEM. The device was characterized by I-V, QE and Mott-Schottky (capacitance-voltage) plot.

The novel chlorogermyliumylidene complex L[ClGe:](+) (L = 1,8-bis(tri-n-butylphosphanzenyl)naphthalene) with a 'naked' Cl(-) as a counter anion was synthesized through reaction of L with Cl(2)Ge: and fully characterized. Its reaction with elemental sulfur afforded the first germathionium [ClGe=S](+) cation containing species. The latter has also been fully characterized, including single-crysta...

The chemistry of complexes with diatomic chalcogen ligands has attracted much attention due to their unique structure, biological interest, potential for hydrogen-transfer catalysis, and synthetic utility as a precursor of new metal cluster complexes. However, since sulfur and selenium ligands have a strong propensity for bridging metal atoms, it is often difficult to prepare their mononuclear ...

Hydrogenobacter thermophilus is a thermophilic, obligately chemolithoautotrophic and aerobic hydrogen-oxidizing bacterium. It is unique in its ability to fix carbon dioxide via the reductive tricarboxylic acid cycle under aerobic conditions. It utilizes molecular hydrogen, elemental sulfur, or thiosulfate as the sole energy source. Here, we report the complete genome sequence of H. thermophilus...

Benzyne is shown to add elemental sulfur and give rise to a series of polysulfane compounds. A computational and experimental study is presented. Odd-membered o-C6H4Sx rings (x = 1-8), except x = 1, which suffers from ring strain, have enhanced stability compared to even-membered rings. The acquisition of "odd-even" data may shed new light, revealing patterns on polysulfane stability and struct...

X-ray microprobes (XRM) coupled with high-brightness synchrotron X-ray facilities are powerful tools for environmental biogeochemistry research. One such instrument, the XRM at the Geo Soil Enviro Center for Advanced Radiation Sources Sector 13 at the Advanced Photon Source (APS; Argonne National Laboratory, Lemont, IL) was recently improved as part of a canted undulator geometry upgrade of the...

Mechanistic analysis of the reaction between elemental sulfur or selenium and 1,3-dialkylimidazolium acetate ionic liquids, in the absence of an external base or solvent, affords evidence for the equilibrium presence of carbene species in these ionic liquids. It demonstrates the potential to control, through anion selection, the concentration of carbene in stable ionic liquids.

The solvothermal reaction of elemental zinc with sulfur in ethylenediamine (en) as solvent yields [ZnS-0.5(NH2CH2CH2NH2)], 1, an unprecedented ethylenediamine pillared ZnS layered compound, containing two dimensional (2-D) boat-type 6-membered rings, which was characterized by ab initio structure solution from powder diffraction data (SDPD).

Elemental sulfur (S8) was found to react with [(TMPA)CuI(CH3CN)]+ to form the trans-mu-1,2 end-on disulfide complex [(TMPA)Cu-S-S-Cu(TMPA)]2+. The X-ray structure of this centrosymmetric disulfide complex shows a Cu(1)-S(1) bond length of 2.280(2) A and a S(1)-S(1A) bond length of 2.044(4) A.