Introduction ASD are heterogeneous pathological conditions characterized by difficulties in establishing social contacts and the manifestation of repetitive behavior. An atypical trajectory brain maturation, impaired neurogenesis, synaptogenesis, an imbalance excitatory inhibitory systems CNS form morphofunctional basis ASD. Objectives To understand functioning this complexly organized system t...

objective: although metabolic diseases individually are rare ,but overall have an incidence of 1/2000 and can cause devastating and irreversible effect if not diagnosed early and treated promptly. selective screening is an acceptable method for detection of these multi presentation diseases.method: using panel neonatal screening for detection of metabolic diseases in 650 high risk iranian patie...

materials and methods one hundred sixty five units which provide mammography examination services were included in the audit. samples of mammographic examinations conducted between july 1st and december 31st, 2012 were evaluated. auditors completed web-based evaluation forms, including quality parameters and descriptive statistics on the patients and institutions. conclusion the audit showed si...

objectives: monitoring development in infancy results in early detection of developmental delay, and early intervention can prevent sever complications of developmental disorders. the purpose of this study was to determine quality of developmental screening of 3-12 months infants referred to tehran health centers, through comparing with screening by bayley infant neurodevelopmental screener ii ...

Currently, drug screening relies on cell-based experiments or on animal models to confirm biological effects. The mammalian system is considered too time-consuming, expensive and complex to perform high-throughput drug screening. There is a gap between in vitro cell-based models and the in vivo mammalian models. The zebrafish is an ideal model that could link preclinical toxicity screening with...