BACKGROUND Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease often causing decreased quality of life, social withdrawal and unemployment. Studies examining the effect of pharmacological interventions demonstrated only minor effects, whereas non-pharmacological interventions as e.g. patient education programs have shown promising results. OBJECTIVE We aim to systematical...

OBJECTIVE The objective of this study was to assess the quality of life (QoL) in patients with head-and-neck paragangliomas ('glomus tumors'). DESIGN We conducted a case-control study. METHODS We assessed QoL in 82 patients with head-and-neck paragangliomas using four validated health-related questionnaires: Hospital Anxiety and Depression Scale, Multidimensional Fatigue Index (MFI-20), Sho...

OBJECTIVE The aim of this study is to estimate the association of shortness of breath (SOB), fatigue and bilateral lower limb edema (LLE) - typical symptoms of HF - with quality of life (QOL) dimensions, measured by the Medical Outcomes Study 36-Item Short Form Health Survey (SF-36). METHODS This cross-sectional study was conducted as part of the CAMELIA study (Cardiometabolic Renal Familial ...

It is easy for the internet learners to generate learning fatigue because of the long-term lack of emotional interaction in the learning process, and learning fatigue often manifests through the eye condition, in order to do effective monitoring for remote intelligent tutoring system, the learning fatigue eye state recognition algorithm is put forward based on Gabor wavelet and HMM. The algorit...

BACKGROUND Gulf War exposures in 1990 and 1991 have caused 25% to 30% of deployed personnel to develop a syndrome of chronic fatigue, pain, hyperalgesia, cognitive and affective dysfunction. METHODS Gulf War veterans (n = 31) and sedentary veteran and civilian controls (n = 20) completed fMRI scans for diffusion tensor imaging. A combination of dolorimetry, subjective reports of pain and fati...

BACKGROUND AND PURPOSE Many patients who survive an aneurysmal subarachnoid hemorrhage experience decreased health-related quality of life (HRQoL). Physical factors have been identified as determinants of HRQoL. We describe long-term HRQoL and assessed whether psychological symptoms and personality characteristics determine HRQoL after subarachnoid hemorrhage. METHODS In a cross-sectional stu...

INTRODUCTION Several reports indicate that inflammation may play a role in depression and demonstrate enhanced systemic levels of inflammatory mediators. We hypothesized that 44 patients with a diagnosis of depression would present with a specific and different serum and cerebrospinal fluid (CSF) cytokine profile compared to 21 patients with diffuse neurological symptoms, of whom 15 had fatigue...

OBJECTIVE To study factors related to quality of life after a hypoxic period due to cardiac arrest. DESIGN Retrospective cohort study. SUBJECTS Eighty-eight survivors of out-of-hospital cardiac arrest, admitted to a Dutch academic hospital between 2001 and 2006. METHODS Patients received a set of questionnaires at home. The main outcome measures were physical and mental quality of life (M...

Cancer is related to a deterioration of nutritional status and quality of life (QoL), but the extent of these conditions in patients with Non Small Cell Lung Cancer (NSCLC) has not been studied. The aim of the present study was to assess the association between QoL and undernutrition in NSCLC patients. Nutritional status was evaluated with Patient Generated - Subjective Global Assessment and Qo...