The process of implantation is an interactive cascade of events between the embryo and the endometrium. It is a dynamic process consisting of three distinct phases. They are (i) apposition of embryo (ii) attachment with the epithelial lining of the endometrium and (iii) invasion into the endometrial stroma gaining access to the maternal circulatory system. Embryo implantation failure may occur ...

Introduction: Although the effect of adriamycin, a chemical drug used to treat cancer, is known to affect gametogenesis and ovarian function, the drug’s effect on endometrial receptivity and expression of integrin genes is unclear. To fill this gap, we aimed to investigate the effect of adriamycin on the expression of integrin genes that play a role in endometrial receptivity. Methods: A total...

Embryo implantation is essential for mammalian pregnancy, which involves intricate cross-talk between the blastocyst and the maternal endometrium. Recent advances have identified various molecules crucial to implantation and endometrial receptivity, including leukemia inhibitory factor, calcitonin, and homeobox A10. There is a close relationship between implantation and inflammation. Lipoxins, ...

Abstract Study question Is there an influence of Lactobacillus relative abundance on the expression profile a set genes related to endometrial receptivity? Summary answer The genus in endometrium does not affect key receptivity determination. What is known already Typically, eubiosis has been determined by dominant presence (at least 90%), whereas lower this considered as dysbiosis. However, re...

The effect of Shoutai pill on endometrial receptivity was analyzed. A total of 160 patients with spontaneous abortion were enrolled in this study. They were treated in the Fifth People's Hospital of Jinan (Shandong, China) from February 2014 to June 2016. The following treatment regimen was performed for the patients: after menstruation, Shoutai pill was taken as continuous medication for more ...

BACKGROUND Metformin has been shown to improve fertility in anovulatory patients with polycystic ovary syndrome (PCOS), inducing not only a high ovulation and pregnancy rate but also reducing the incidence of miscarriages. The aim of the present study was to evaluate the uterine effects of metformin in patients with PCOS who ovulated under metformin. METHODS Thirty-seven non-obese primary inf...

BACKGROUND In the endometrium the steroid hormone progesterone (P), acting through its nuclear receptors, regulates the expression of specific target genes and gene networks required for endometrial maturation. Proper endometrial maturation is considered a requirement for embryo implantation. Endometrial receptivity is a complex process that is spatially and temporally restricted and the identi...