نتایج جستجو برای: endothelial differentiation
تعداد نتایج: 350794 فیلتر نتایج به سال:
The concept of tissue-restricted differentiation of postnatal stem cells has been challenged by recent evidence showing pluripotency for hematopoietic, mesenchymal, and neural stem cells. Furthermore, rare but well documented examples exist of already differentiated cells in developing mammals that change fate and trans-differentiate into another cell type. Here, we report that endothelial cell...
BACKGROUND Stem cell therapy for the treatment of vascular-related diseases through functional revascularization is one of the most important research areas in tissue engineering. The aim of this study was to investigate the in vitro differentiation of umbilical CL-MSC into endothelial lineage cells. METHODS In this study, isolated cells were characterized for expression of MSC-specific marke...
AIM To compare the adhesion, migration and endothelial differentiation potential of peripheral blood-derived mononuclear cells (PBMCs) obtained from drug-naive normal glucose tolerance (NGT) and impaired glucose tolerance (IGT) Asian Indian men. METHODS Based on the 75-g oral glucose tolerance test, 30 NGT and 31 IGT subjects were recruited into the study. PBMCs were isolated from fasting blo...
Endothelial integrity or homeostasis is not only essential for regulating arterial activity and vascular tone under physiological conditions, but also critical for triggering various cardiovascular diseases including atherosclerosis and balloon angioplasty if such a balance has been impaired. Moreover, endothelial cell development and differentiation are key steps during embryogenesis and invol...
objective(s):to know whether scurrula atropurpurea is able to modulate total plasma nitrate/nitrite levels, decrease endothelial damage, and increase endothelial progenitor cells (epcs) in hypertensive rats. materials and methods: the rats were divided in 5 groups: control (normotensive) group, desoxy cortico sterone (doca)-salt hypertensive group, and three doca-salt hypertensive groups. all 5...
Abstract Breast angiosarcoma is a rare malignancy of endothelial origin that can be categorized as primary (PAS) or secondary (SAS) based on etiology. Primary typically affects younger women with no known risk factors, whereas SAS the breast develops in older who have undergone cancer treatment. There are two types SAS, one setting chronic lymphedema and radiation-associated neoplasm after brea...
INTRODUCTION The aim of this study is to determine whether regulation of the expression level of fms-like tyrosine kinase-4 (Flt-4) is related to osteoclast differentiation. MATERIAL AND METHODS Osteoclast formation and differentiation of mouse bone marrow cells and RAW264.7 cells were performed. To induce osteoclast differentiation, RANKL (50 ng/ml) with or without vascular endothelial growt...
Endothelial-like differentiation (ELD) of dendritic cells (DCs) is a poorly understood phenomenon. The present study evaluated the effect on the ELD of DCs by using human esophageal squamous cell carcinoma (ESCC) cells with high or poor differentiation. The results demonstrated that KYSE450 (highly differentiated) and KYSE70 (poorly differentiated) cell supernatants induce the differentiation o...
Formation of the vascular system requires differentiation and patterning of endothelial and smooth muscle cells (SMCs). Although much attention has focused on development of the vascular endothelial network, the mechanisms that control vascular SMC development are largely unknown. Myocardin is a smooth and cardiac muscle-specific transcriptional coactivator of serum response factor, a ubiquitou...
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