Background: Outer membrane proteins (OMPs) constitute the main structure and about half of the cell wall of Gram-negative bacteria. The OMPs of Escherichia coli (E. coli) play an important role in its drug resistance. Previous studies have shown that the OMPs of E. coli enhance its pathogenic effects by helping the bacterium to evade the immune defense and promote its adsorption to host cells. ...

in this study 130 bulk tank milk samples which were delivered to the pegah pasturisation factory inmashhad were collected randomly during the summer months. samples were firstly enriched in modifiedtrypticase soy broth containing novobiocin, followed by plating onto sorbitol macconkey agar supplementedwith cefixime and potassium tellurite for isolation of escherichia coli o157:h7. consequently ...

tissue plasminogen activator (tpa) is a serine protease, which is composed of five distinct structural domains with 17 disulfide bonds, representing a model of high-disulfide proteins in human body. one of the most important limitations for high yield heterologous protein production in escherichia coli (e. coli) is the expression of complex proteins with multiple disulfide bridges. in this stud...

To assess public health risks from environmental exposure to Extended-Spectrum β-Lactamases (ESBL)-producing bacteria, it is necessary to have insight in the proportion of relative harmless commensal variants and potentially pathogenic ones (which may directly cause disease). In the current study, 170 ESBL-producing E. coli from Dutch wastewater (n = 82) and surface water (n = 88) were characte...

conclusions this is the first report on isolation and identification of two novel lytic myovirus and podovirus from zayandehrood river in isfahan that had lytic effects on e. coli ptcc1399 and e. coli sbswf27 strains as well as coliform's population of isfahan municipal wastewater. we suggest that the use of these lytic coliphages for reduction of coliform's population in sewage could be consid...

objective: aminoglycosides are highly potent, broad-spectrum antibiotics with many desirable properties for the treatment of life-threatening infections. escherichia coli (e. coli) is the most common cause of urinary tract infection (uti). antibiotic resistance has recently become prevalent. enzymatic inactivation of aminoglycosides by aminoglycoside-modifying enzymes is the main mechanism of r...

Live attenuated bacteria have been used as target vehicles for genetic therapy of malignant carcinoma because they can be reprogrammed by following simple rules and the ability to tumor hypoxic region. In this research, noninvasive Escherichia coli (E. Coli) is genetically modified through plasmid transfection afford E. Coli(p) with overexpressed human catalase catalyzing H2O2 into O2 in site. ...

this study was designed to compare the efficacy of a phytobiotic containing a mixture of essential oils of oreganum aetheroleum and an antibiotic containing ciprofloxacin as an active principle for the treatment of experimental escherichia coli (e. coli) infection in broiler chickens. two-hundred-day-old broiler chickens were divided into 5 equal groups. the 1st group was neither challenged nor...