نتایج جستجو برای: enzyme inhibition assay

تعداد نتایج: 702362  

Journal: :research in pharmaceutical sciences 0

considering the emergence of antibiotic resistance, scientists are interested in using new antimicrobial agents in the treatment of infectious diseases including infections of the enteric systems. lactic acid bacteria have the great potential to produce antimicrobial compounds that inhibit and control pathogenic bacteria. the aim of this study was to determine the anti-bacterial and anti-adhere...

2014
Keith H Ansell Hayley M Jones David Whalley Alisdair Hearn Debra L Taylor Emmanuel C Patin Timothy M Chapman Simon A Osborne Claire Wallace Kristian Birchall Jonathan Large Nathalie Bouloc Ela Smiljanic-Hurley Barbara Clough Robert W Moon Judith L Green Anthony A Holder

PfCDPK1 is a Plasmodium falciparum calcium-dependent protein kinase, which has been identified as a potential target for novel antimalarial chemotherapeutics. In order to further investigate the role of PfCDPK1, we established a high-throughput in vitro biochemical assay and used it to screen a library of over 35,000 small molecules. Five chemical series of inhibitors were initially identified ...

Journal: :Journal of bacteriology 1964
W H TAYLOR M L TAYLOR

Taylor, W. Herman (Portland State College, Portland, Ore.), and Mary L. Taylor. Enzymes of the pyrimidine pathway in Escherichia coli. II. Intracellular localization and properties of dihydroorotic dehydrogenase. J. Bacteriol. 88:105-111. 1964.-Intracellular localization of three enzymes of the pyrimidine pathway in Escherichia coli was studied. Dihydroorotic dehydrogenase was found to be assoc...

Journal: :Clinical and diagnostic laboratory immunology 2005
Carmel Taylor Russell Simmons Ina Smith

We report the development of a flavivirus immunoglobulin M (IgM) capture enzyme-linked immunosorbent assay (MAC-ELISA) which improves the determination of an infecting flavivirus serotype over that by current serological methods. A panel of 165 IgM-positive sera from flavivirus patients with specific diagnostic results was tested by the flavivirus MAC-ELISA using a panel of 10 antigens. For 134...

Journal: :Journal of clinical microbiology 1981
I C Shekarchi J L Sever N Tzan A Ley L C Ward D Madden

The hemagglutination inhibition test (HAI) and the enzyme-linked immunosorbent assay (ELISA) for detecting antibody to rubella virus were compared by testing 25 sets of paired sera taken before and after infection and 10 sets of sera taken during acute and convalescent stages of the disease and by screening 700 serum samples from the Collaborative Perinatal Project, NIH/NINCDS. The tests were f...

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