The purpose of this study was to compare the range of motion (ROM) and strength of the metacarpophalangeal (MP) and interphalangeal (IP) joints among massage practitioners with and without thumb pain and control subjects. Sixteen massage practitioners with thumb pain, 16 practitioners without thumb pain, and 16 control subjects participated in this study. ROM of flexion, extension, and abductio...

The stratum corneum is composed of protein-enriched corneocytes embedded in an intercellular matrix of nonpolar lipids organized as lamellar layers and giving rise to epidermal permeability barrier (EPB). EPB defects have an important role in the pathophysiology of skin diseases such as eczema. The transcriptional control of skin lipid metabolism is poorly understood. We have discovered that mi...

Inhibiting of Proprotein Convertase Subtilisin/Kexin-type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR) binding is an effective way for reducing Low Density Lipoprotein cholesterol (LDL-C). Understanding the interaction between PCSK9 and LDLR is useful for PCSK9 inhibitor design. In this work, MD simulations with the standard (non-polarizable) AMBER force field and effective polarizable...

Abstract In conflict studies, environmental peacebuilding (EPB) has become an established concept to explain how cooperation among opposing parties provides a platform for peacebuilding. EPB literature been shaped predominantly by political science perspectives, initially with focus on interstate conflicts, and ecological dynamics have received little attention date. Building the Social-Ecologi...

The penetration characteristics of the slurry and support pressure transfer mechanisms are critical to tunnel face stability control during a mechanized excavation. In this paper, numerical calculations coupling computational fluid dynamics (CFD) with discrete element method (DEM) carried out simulate sand column tests considering different particle size ratios. reasonableness model is verified...