CLOVES syndrome is a complex disorder of congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal/scoliosis/spinal anomalies. We report the occurrence of spinal-paraspinal fast-flow lesions within or adjacent to the truncal overgrowth or a cutaneous birthmark in 6 patients with CLOVES syndrome.

Cap polyposis is extremely rare in children. We report a case of an 11-month-old male infant who visited our hospital because of rectal prolapse and small amount of hematochezia lasting several days. He also had an epidermal nevus in the sacral area. Colonoscopy showed erythematous, multilobulated, circumferential, polypoid lesions with mucoid discharge from the rectum. He was diagnosed with ca...

Background: Verrucous epidermal nevi (VEN) are benign congenital epidermal hyperplasia and they constitute the most frequent form of epidermal nevi. Verrucous epidermal nevi lesions typically occur on the trunk or extremities but may also occur on the face and neck. The lesions may vary from skin colored to brown. No ideal treatment is yet available.

Spitz nevus is a variant of melanocytic nevus which is histopathologically defined as large spindle and/or epithelioid cells. Angiomatoid Spitz nevus is a rare histologic variant of desmoplastic Spitz nevus characterized by prominent vasculature. We present a case of angiomatoid Spitz nevus, celluar type, that has not been reported before. We provide another example to show the remarkable diver...

Blue nevus is a benign melanocytic lesion, typically asymptomatic and of unknown etiology. Many histological subtypes are recognized, the most commons being: common blue nevus, cellular blue nevus, and combined blue nevus. New rare variants have been described in the literature, with emphasis on eruptive blue nevus, plaque, agminate, linear, with satellitosis, disseminated, familial and targeto...

Verrucous epidermal nevi are congenital hamartomas composed of keratinocytes and may occur alone or in association with developmental abnormalities. A close relationship between variations in the PIK3CA and FGFR3 genes and the appearance of nevi has been recently reported. Based on that, we performed molecular assays for the identification of E542K, E545G/K and H1047R mutations in the PIK3CA ge...

Blaschko-linear psoriasis (PBL) is a rare form of that presents as longitudinal lines on the skin, along Blaschko lines. This often observed in children and can be difficult to distinguish from other acquired linear dermatoses such inflammatory verrucous epidermal nevus (ILVEN) lichen striatus. The prevalence PBL unknown, but it generally more common boys than girls. clinical histological simil...

Dysplastic nevus is an acquired or hereditary nevus that clinically seems atypical and pathohistologically dysplastic. The term of dysplastic nevus has changed through history and even until now the dermatologists and pathologists have not found the same conclusion for name and definition of dysplastic nevus. Epidemiology of dysplastic nevus is different depending on geographic lattitude, being...

Dermoscopy is a practical, non-invasive tool that can be used to distinguish tinea nigra from other lesions appear macroscopically similar, including acral nevus. Under dermoscopy, presents with pattern of spiculated gray-brown pigment deposition, whereas nevus most often as brown deposition in parallel furrow pattern.

BACKGROUND A verrucous epidermal nevus (VEN) is a skin disorder that has been treated using different treatment modalities with varying results. Ablative lasers such as carbon dioxide laser (CO2) and erbium:yttrium-aluminum-garnet (Er:YAG) laser have been considered as the gold standard for the treatment of epidermal nevi. OBJECTIVE To evaluate and compare the efficacy, postoperative wound he...