Cellular resting and action potentials and total tissue concentrations of K + , Na + , and Ch were measured in canine myocardial and Purkinje tissues. The results with myocardium were consistent with those of others: the total tissue concentration of K was greater than that of Na of Ch. In Purkinje tissue, the total tissue concentration of K was relatively low, while that of Na and of Ch was hi...

Diffusion, partitioning, and binding of two aldose-reductase inhibitors (ARI) in the rat lens were investigated under in vitro conditions. A lipophilic ARI (CT-112) and a hydrophilic ARI (AD-5467) were used as model drugs. Under lens-uptake conditions, the drug concentration in the lens increased rapidly during the initial 10 hr and reached steady state (equilibrium) after 24 hr. Despite the eq...

The highest concentration of radon (222 Rn) and thoron (220 Rn) in indoor environment is a major health hazard for man (1) as a result many researchers (2–4) are interested to estimate indoor radon concentration in many countries. In this study, a survey of radon and its daughters has been done to provide data on the hourly, daily and seasonal average indoor radon in Isfahan city dwellings and ...

Twenty-five years ago John P. Peters with Donald D. Van Slyke wrote one of the most precise, lucid, and comprehensive accounts of acid-base equilibrium that has ever appeared in scientific literature, namely, Chapter 18 in Volume I, Interpretations, of Quantitative clinical chemistry." This account rested on the basic experimental work of Van Slyke and other investigators and especially on the ...

We evaluated three one-step (analog) and two two-step radioimmunoassay for free thyroxin (FT4), and a FT4 index calculated from the total T4 (TT4) and thyroxin-binding globulin (TBG) ratio for technical performance, for correlation with the reference FT4 method (equilibrium dialysis), and for dependence on TBG and albumin concentrations. The one-step methods (Amerlex, Coat-A-Count, and GammaCoa...

MALNIC, GERHARD, RUTH M. KL~SE, AND GERHARD GIEBISCH. Microperfusion study of distal tubular potassium and sodium transfer in rat kidney. Am. ,J. Physiol. 2 I I (3) : 548359. 1966. The ability of proximal and distal tubules to establish limiting transepithelial electrochemical potential gradients was tested in stationary microperfusion experiments in vivo. Droplets of isoosmotic rafhnose soluti...