adherens junctions — within the apical junctional region of the Drosophila embryonic epithelium; this may provide mechanical stability during the junctional remodeling that accompanies tissue morphogenesis. Too much or too little ERM-mediated crosslinking impairs the migration of mesendoderm cells during zebrafish gastrulation and homing lymphocytes in mice. This is due in part to the cells’ in...

Erythromycin and tylosin are commonly used in animal production, and such use is perceived to contribute to the overall antimicrobial resistance (AR) reservoirs. Quantitative measurements of this type of AR reservoir in microbial communities are required to understand AR ecology (e.g., emergence, persistence, and dissemination). We report here the development, validation, and use of six real-ti...

The ERM family is composed of the proteins ezrin, moesin and radixin, which are cell structure-related proteins. Despite the detection of viable roles of ERM family proteins, the impact of these molecules in cancer pathogenesis has yet to be investigated. Evidence emerging from clinical and translational studies showed that the ERM family is linked to disease progression in clinical cancers. We...

Members of the Mycobacterium abscessus group (MAG) cause lung, soft tissue, and disseminated infections. The oral macrolides clarithromycin and azithromycin are commonly used for treatment. MAG can display clarithromycin resistance through the inducible erm(41) gene or via acquired mutations in the rrl (23S rRNA) gene. Strains harboring a truncation or a T28C substitution in erm(41) lose the in...

We previously identified an Ets cis-element in the mouse caveolin-1 promoter that is selectively activated in lung epithelial (E10), but not lung endothelial murine lung endothelial cell line (MFLM-4), cell lines and therefore appears important for differential, cell-specific caveolin-1 transcription. In the present study, we demonstrate that immunostaining of adult mouse lung detects the ETS p...

Dear Editor, Although surgical removal of the epiretinal membrane (ERM) in symptomatic patients is frequently performed and provides quite good anatomical and functional results, ERM peeling often causes complications such as cataract formation in phakic eyes, retinal tear or detachment, and macular edema [1]. Choroidal neovascularization (CNV) development after ERM removal is very rare, with o...

We measured the expression of ERM gene, a nuclear transcription factor belonging to the ets family, in a series of 364 unselected primary breast cancers from patients who underwent locoregional surgery in the Centre Oscar Lambret between May 1989 and December 1991. The expression of ERM was quantified with a real-time one-step reverse transcription-PCR assay based on the 5'-nuclease activity of...

OBJECTIVE To study the efficacy of epiretinal membrane (ERM) peeling in eyes with dry age-related macular degeneration (AMD). METHODS We retrospectively analyzed patient charts on 17 eyes (16 patients) that underwent ERM peeling with a concurrent diagnosis of dry AMD. RESULTS Eyes with concurrent dry AMD and with a good preoperative best-corrected visual acuity (BCVA) (better than or equal ...

Employee relationship management (ERM) constitutes an emerging trend of managing human resources by building and maintaining individualized and mutually valuable relationships with employees based on information technology. However, given the early and still emerging state, there is little knowledge and agreement regarding ERM. Hence, the current paper attempts to clarify the concept and derive...

Article History: Received: Apr 20, 2009 Revised: May 6, 2009 Accepted: Jun 12, 2009 methicillin resistance has increased. The efficacy of macrolide antibiotics in the treatment of infections caused by multi-resistant staphylococci makes them the most often prescribed drugs in clinical medicine. How ever, the expanded use of these antibiotics has been accompanied by increased resistance rates am...