نتایج جستجو برای: esophageal carcinoma

تعداد نتایج: 430053  

2017
Yongchen Guo Yonghua Bao Ming Ma Shanshan Zhang Yongmeng Zhang Ming Yuan Bing Liu Yiqiong Yang Wen Cui Emmanuel Ansong Huali Dong Virgilia Macias Wancai Yang

Esophagitis and Barrett's esophagus are linked to esophageal squamous cell carcinoma and adenocarcinoma, respectively. However, the underlying mechanisms are still unclear. This study analyzed the expression levels of and correlation between PLCE1 and PRKCA in human esophagitis, carcinogen NMBA-induced rat esophagus, PLCE1 genetic deficient mouse esophageal epithelial tissues and human esophage...

Journal: :European Journal of Pharmacology 2021

Esophageal cancer is a prominent worldwide illness that divided into two main subtypes: esophageal squamous cell carcinoma and adenocarcinoma. Mortality rates are alarming, the understanding of mechanisms involved in development, becomes essential. Purinergic signaling related to many diseases among these various types tumors. Here we studied effects P2Y2 receptor activation different cancer. t...

Journal: :Journal of The National Comprehensive Cancer Network 2023

Esophageal squamous cell carcinoma is an aggressive malignancy with histologic variability depending on where in the world it diagnosed, most of these cancers occurring China and other parts Asia. Previous studies cytotoxic chemotherapy combinations led to a plateau median overall survival approximately 10 12 months, as well need for more effective treatment options. Cytotoxic served control ar...

2014
Ram Abhinav Kannan

Background Chemoradiation has shown superior overall survival when compared with radiation alone in esophageal carcinoma. Due to compromised nutritional status, radiation therapy in esophageal cancer patients itself is a challenge and addition of concurrent chemotherapy leads to severe side effects even when standard dose regimens are used. The tolerance of chemoradiation for carcinoma esophagu...

2010
Tomoyuki Akiyama Yasunobu Abe Hiroshi Iida Hiroki Endo Kunihiro Hosono Kyoko Yoneda Hirokazu Takahashi Masahiko Inamori Akihide Ryo Shoji Yamanaka Yoshiaki Inayama Atsushi Nakajima

INTRODUCTION Standard endoscopic mucosal resection or endoscopic submucosal dissection is a procedure for patients with minute cancers, complicated with esophageal varices that puts them at high risk of bleeding. CASE PRESENTATION We present the case of a 77-year-old Japanese man with alcoholic cirrhosis who underwent a routine endoscopy examination as a screening procedure for esophageal var...

Journal: :Anticancer research 2010
Stephanie J Gros Thorsten Dohrmann Tamina Rawnaq Nina Kurschat Michael Bouvet Johannes Wessels Robert M Hoffmann Jakob R Izbicki Jussuf T Kaifi

AIM Orthotopic models utilizing orthotopic implantation have been used for developing cancer models of multiple tumor entities. The aim of this study was to evaluate the role of orthotopic injection in establishing a model of esophageal cancer using a human green fluorescent protein (GFP) cell line of human esophageal carcinoma. MATERIALS AND METHODS Nude mice were orthotopically injected in ...

2012
Yusuke Sato Satoru Motoyama Junichi Ogawa

Esophageal cancer is the seventh leading cause of cancer deaths worldwide (410,000 new cases annually)(1). Asian, Middle Eastern, and East African countries have a markedly higher incidence of esophageal cancer than other areas. In the United States, the incidence of adenocarcinoma of the distal esophagus and gastroesophageal junction has progressively increased to approximately 70% of all esop...

2012
Mingzhou Guo Yan Jia Wenji Yan

Esophageal cancer (EC) is the eighth most common cancer and the sixth most common cause of cancer death worldwide. Esophageal squamous cell carcinoma (ESCC) and adenocarcinoma (EAC) are two major histopathological type of esophageal cancer. The incidence of EC was increased in the past 3 decades. Five-year survival of advanced cancer is still very poor, even though improved surgical techniques ...

2016
Masaho Ota Kosuke Narumiya Kenji Kudo Yohsuke Yagawa Shinsuke Maeda Harushi Osugi Masakazu Yamamoto

BACKGROUND Patients with esophageal achalasia are considered to be a high-risk group for esophageal carcinoma, and it has been reported that this cancer often arises at a long interval after surgery for achalasia. However, it is unclear whether esophageal carcinoma is frequent when achalasia has been treated successfully and the patient is without dysphagia. In this study, we reviewed patients ...

Journal: :World journal of gastroenterology 2009
Jón O Kristinsson Paul van Westerveld Rene H M te Morsche Hennie M J Roelofs T Wobbes Ben J M Witteman Adriaan C I T L Tan Martijn G H van Oijen Jan B M J Jansen Wilbert H M Peters

AIM To determine whether -1195 A-->G and/or -765 G-->C polymorphisms in Cyclooxygenase-2 (COX-2) may have a risk modifying effect on the development of esophageal carcinoma in a Dutch Caucasian population. METHODS Two study groups were recruited, 252 patients with esophageal carcinoma and 240 healthy controls, matched for race, age, gender and recruiting area. DNA was isolated from whole bloo...

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