The esterification reaction of trimellitic anhydride chloride TMAC 1 with N-(hydroxymethyl) phthalimide NHMP 2, N-(2-hydroxyethyl) phthalimide NHEP 3 or N-(hydroxymethyl) thalidomide NHMT 4 afforded novel cyclic imide-ester derivatives; phthaloyl-phthalic anhydride methyl ester PPAME 5, phthaloyl-phthalic anhydride ethyl ester PPAEE 6 and thalidomide-phthalic anhydride methyl ester TPAME 7, res...

chyuri (Diploknema butyracea (roxburgh) H. J. lam) is widely used in nepal for its medicinal properties and as a source of chyuri ghee (fat) extracted from the seeds. the main purpose of the present study was the gc-MS analysis of fatty acids in seed fat of chyuri after acidic methanolysis. Palmitic acid methyl ester (1), linoleic acid methyl ester (2), oleic acid methyl ester (3) and steric ac...

We report the asymmetric synthesis of di-3-pentyl (3S,alphaS,7E)-3-N-benzyl-N-alpha-methylbenzylamino-dec-7-enedioate (9), which contains the correct functionalization to produce delta-amino acid derivatives to be used as monomers for Peptide Nucleic Acid (PNA) formation With this aim, thymine-pentanoic acid 15 and some of its ester derivatives were obtained, their reactivity was studied and th...

The sulfurous acid ester, trans-sulfurous acid allyl ester 3-allylsulfanyl-allyl ester 8, along with two known thiosulfinates was isolated from the aqueous ethanol extract of garlic (Allium sativum). The chemical structure of 8 was determined on the basis of spectroscopic data including high resolution mass and two-dimensional NMR techniques. All of these compounds induced methemoglobin formati...

The rate of secretion of apoB-100-containing lipoprotein particles by HepG2 cells is determined to an important extent by post-translational mechanisms, the mass of neutral lipids clearly playing a role in this process. Our previous data indicated that cholesteryl ester might influence the proportion of newly synthesized apoB-100 molecules that are incorporated into nascent lipoproteins rather ...

introduction: the treatment of cutaneous leishmaniasis (cl) is based primarily on the use of pentavalent antimonials, which may lead to many side effects limiting their use. photodynamic therapy (pdt) is an alternative for the treatment of cl, and some xanthene dyes have the potential for use in pdt. methods: the xanthenes rose bengal b (rb) and its derivatives rose bengal methyl ester (rbmet),...

The anionic ring-opening polymerizations (AROP) of bio-based N-acetyl homocysteine thiolactone (NHTL) and different epoxides were carried out using benzyl alcohol 2-tert-butylimino-2-diethylamino-1,3-dimethylperhydro-1,3,2-diazaphosphorine (BEMP) as initiating system. This polymerization is a rare example AROP in the presence an acidic moiety (acetamido group). Well-defined alternating poly(est...

Two new triterpenoid glycosides were isolated (one of them as the methyl ester) as major components from leaves of Ilex chinensis Sims (Aquifoliaceae) . The structures of these glycosides, termed ilexoside A (1) and ilexoside B methyl ester (2a), have been established to be 3ƒÀ-ƒ-(ƒÀ-Dxylopyranosyl)siaresinolic acid and 3ƒÀ-ƒ-(ƒÀ-D-xylopyranosyl)pomolic acid methyl ester , respectively, based o...