نتایج جستجو برای: ethyl alcohol
تعداد نتایج: 148372 فیلتر نتایج به سال:
Alcohol dependence is a common, complex and debilitating disorder with genetic and environmental influences. Here we show that alcohol consumption increases following mutations to the γ-aminobutyric acidA receptor (GABAAR) β1 subunit gene (Gabrb1). Using N-ethyl-N-nitrosourea mutagenesis on an alcohol-averse background (F1 BALB/cAnN x C3H/HeH), we develop a mouse model exhibiting strong heritab...
Occupational exposure to ethylene oxide was assessed among the workers remaining in direct contact with ethylene oxide or with ethylene oxide-sterilized instruments in 13 hospitals located in the city of Lódź and its suburbs. Individual dosimetry and stationary sampling methods were employed. The samples collected from the occupational environment were analysed by gas chromatography with mass d...
Mechanisms responsible for alcohol-induced heart muscle disease have been difficult to elucidate partly because of previously obscure, demonstrable cardiac metabolism of ethanol. Recently, fatty acid ethyl esters were identified in our laboratory and found to be myocardial metabolites of ethanol. In the present study, they have been shown to induce mitochondrial dysfunction. Incubation of isola...
Heterogeneous esterification of 2-ethyl-1-hexanol and 2-ethyl hexanoic acid using AMBERLYST 15 as solid acid-catalyst in supercritical carbon dioxide (SC-CO2) has been studied. Effect of pressure (150, 200, and 250 bar), temperature (75, 110, and 140 C), flow rate of liquid CO2 (0.4, 0.6, and 0.8 mL.min), type of sample collection, and mole ratio of alcohol to acid (2:1, 1:1, and 1:2) on ester ...
BACKGROUND Chronic alcohol exposure alters the function of alveolar macrophages (AM), impairing immune defenses in both adult and neonatal lungs. Fatty acid ethyl esters (FAEEs) are biological markers of prenatal alcohol exposure in newborns. FAEEs contribute to alcohol-induced mitochondrial (MT) damage in multiple organs. We hypothesized that in utero ethanol exposure would increase FAEEs in t...
Background. A glycoside derivative of indolocarbazole LHS-1269, one the new drugs selectively affecting tumors, which was first synthesized at N.N. Blokhin National Medical-Research Center Oncology Ministry Health Russia, is particular scientific interest. Experimental studies demonstrated a multi-target mechanism action this compound. LHS-1269 interacts with several intracellular targets and i...
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