of AF performance. that contain EG has been reponed to result in irreversible damage to renal, hepatic, cardiovascular, and central nervous systems, and is a cause of death in household pets and other animals.2-4 It is not known why some animals ingest EGcontaining products. Although there are reports suggesting that the "sweet" taste of EG, and of products containing it, may lead to ingestion ...

Clinical and forensic laboratories frequently have to face cases of severe intoxication from ethylene glycol, because of its wide availability, and thus its use as an additive in various housekeeping and commercial products such as anti-freezing agent, car batteries and solvents for dyes. The majority of ethylene glycol poisonings is related to suicide attempts (intentional ingestion) and to mi...

Ethylene glycol, methanol, and diethylene glycol are readily available in many household and commercially available products. While these alcohols are relatively nontoxic themselves, their acidic metabolites are toxic and can result in significant morbidity and mortality. Herein we report a lethal case of massive ethylene glycol ingestion in a suicide with a record high level (1254 mg/dL) and i...

An accurate mass determination method utilizing electrospray ionization mass spectrometry is described for analysis of several different types of phosphoramidites that are extremely acid-sensitive compounds. An earlier method, which applied a LiCl/acetonitrile system, was extended for this special application by using polymeric standards including poly(ethylene glycol) (PEG), poly(ethylene glyc...

A presumptive diagnosis of secondary ethylene glycol toxicity in a female Turkey vulture (Cathartes aura) was made depending on the histopathological changes found in the renal tubules and presence of Isospora spp. of non-avian type within the colon. To the best of our knowledge, this is the first reported case of possible secondary ethylene glycol toxicity in a Turkey vulture in Louisiana Stat...

This paper uses self-assembled monolayers on gold as a model system to demonstrate that the attachment and spreading of Swiss 3T3 fibroblasts depends strongly on the microenvironment of immobilized RGD peptides. This work utilized monolayers that present mixtures of Arg-Gly-Asp peptides, which are ligands for cellular integrin receptors, and oligo(ethylene glycol) groups, which resist the nonsp...

Background: Chitinases (EC.3.2.1.14) hydrolyze the β-1,4-linkages in chitin, an abundant Nacetyl-β-D-glucosamine polysaccharide that is a structural component of protective biological matrices such as insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 (GH18) family of chitinases is an ancient gene family widely expressed in archea, prokaryotes and eukaryotes. Mammals are not ...