Macromolecule release from poly(d,l-lactide-co-glycolide) (PLGA) microspheres has been well-characterized, and is a popular approach for delivering bioactive signals from tissue-engineered scaffolds. However, the effect of some processing solvents, sterilization, and mineral incorporation (when used in concert) on long-term release and bioactivity has seldom been addressed. Understanding these ...

AML1, a gene on chromosome 21 encoding a transcription factor, is disrupted in the (8;21)(q22;q22) and (3;21)(q26;q22) chromosomal translocations associated with myelogenous leukemias; as a result, chimeric proteins AML1/ETO(MTG8) and AML1/Evi-1 are generated, respectively. To clarify the roles of AML1/ETO(MTG8) and AML1/Evi-1 in leukemogenesis, we investigated subcellular localization of these...

ABSTRACT In semiarid regions with greater climatic variability, including prolonged droughts and delayed rainy seasons, supplemental irrigation is critical to ensuring yields of forage cactus pear. The objective was evaluate root distribution nutrient concentration accumulation in ‘Gigante’ pear subjected different regimes. Seven regimes were tested: no (rainfed); five liters medium-salinity wa...

A compreensão da dinâmica entre evapotranspiração de referência (ETo), cultura (ETc) e coeficiente (Kc) fundamental em irrigação. O objetivo deste trabalho foi analisar a relação uma base dados ETc cana-de-açúcar medidos por um lisímetro pesagem eletrônico grande porte Kc ETo calculados. está instalado área localizada na cidade Piracicaba, SP, cultivo cana-planta cultivar RB867515. Para análise...

The obligatory path towards a lean manufacturing organization requires assessment and monitoring. However, framework is not yet available for the engineer to order (ETO) scenario. This work explored ten ETO maturity principles—identified from literature—that take insight three formally defined sets (Toyota Way, construction, product development principles). A practical model was proposed based ...

abstract in order to estimate the reference evapotranspiration different equation is used. validity of each methods depends upon the climate and the parameters which are used in these equations. therefore it is necessary to calibrate these methods for any specific area and for any desired frequency. in this study common temperature and radiation based methods were used for calculating crop evap...