نتایج جستجو برای: eukaryotes

تعداد نتایج: 15076  

Journal: :Cell 2007
Meenakshi K. Doma Roy Parker

Eukaryotic cells contain numerous RNA quality-control systems that are important for shaping the transcriptome of eukaryotic cells. These systems not only prevent accumulation of nonfunctional RNAs but also regulate normal mRNAs, repress viral and parasitic RNAs, and potentially contribute to the evolution of new RNAs and hence proteins. These quality-control circuits can be viewed as a series ...

Journal: :Genome research 2000
G D Stormo

The goal of this paper is to introduce the methods commonly used for predicting protein-coding regions in eukaryotic DNA, primarily for the benefit of those not familiar with the topic. This is not meant as a comprehensive review, nor do I describe in detail the underlying mathematical formalism. Those seeking additional information are encouraged to read some recent reviews (Fickett 1996; Clav...

Journal: :The Journal of eukaryotic microbiology 2012
Sina M Adl Alastair G B Simpson Christopher E Lane Julius Lukeš David Bass Samuel S Bowser Matthew W Brown Fabien Burki Micah Dunthorn Vladimir Hampl Aaron Heiss Mona Hoppenrath Enrique Lara Line Le Gall Denis H Lynn Hilary McManus Edward A D Mitchell Sharon E Mozley-Stanridge Laura W Parfrey Jan Pawlowski Sonja Rueckert Laura Shadwick Conrad L Schoch Alexey Smirnov Frederick W Spiegel

This revision of the classification of eukaryotes, which updates that of Adl et al. [J. Eukaryot. Microbiol. 52 (2005) 399], retains an emphasis on the protists and incorporates changes since 2005 that have resolved nodes and branches in phylogenetic trees. Whereas the previous revision was successful in re-introducing name stability to the classification, this revision provides a classificatio...

2003
S. Burnasheva Hideo Mohri

As recognized by Irene Manton (1) at the time that the basic 9 + 2 structural uniformity of cilia and most eukaryotic flagella was first becoming recognized, these organelles are sufficiently complex that knowledge of their structure, no matter how detailed, cannot provide an understanding of their mechanisms of growth and function . In our understanding of these mechanisms, the substantial adv...

Journal: :Cell 1995
Clare A Beelman Roy Parker

Based on the above mechanisms of mRNA degradation, an integrated model of mRNA turnover can be proposed (Figure 1). In this model, all polyadenylated mRNAs would be degraded by the deadenylation-dependent pathway at some rate. In addition to this default pathway, another layer of complexity would come from degradation mechanisms specific to individual mRNAs or to classes of mRNAs. Such mRNA-spe...

Journal: :Current Biology 2004
Alastair G.B. Simpson Andrew J. Roger

The diversity of life has generally been divided into a few — four to six — fundamental ‘kingdoms’. The most influential system, the ‘Whittaker’ five kingdom structure, recognises Monera (prokaryotes) and four eukaryotic kingdoms: Animalia (Metazoa), Plantae, Fungi and Protista. Whittaker’s system, somewhat modified, was presented as more realistic than the traditional division of life into ani...

Journal: :Current opinion in genetics & development 2000
H Philippe A Germot D Moreira

Molecular phylogeny has been regarded as the ultimate tool for the reconstruction of relationships among eukaryotes-especially the different protist groups-given the difficulty in interpreting morphological data from an evolutionary point of view. In fact, the use of ribosomal RNA as a marker has provided the first well resolved eukaryotic phylogenies, leading to several important evolutionary ...

Journal: :Science 2000
G M Rubin M D Yandell J R Wortman G L Gabor Miklos C R Nelson I K Hariharan M E Fortini P W Li R Apweiler W Fleischmann J M Cherry S Henikoff M P Skupski S Misra M Ashburner E Birney M S Boguski T Brody P Brokstein S E Celniker S A Chervitz D Coates A Cravchik A Gabrielian R F Galle W M Gelbart R A George L S Goldstein F Gong P Guan N L Harris B A Hay R A Hoskins J Li Z Li R O Hynes S J Jones P M Kuehl B Lemaitre J T Littleton D K Morrison C Mungall P H O'Farrell O K Pickeral C Shue L B Vosshall J Zhang Q Zhao X H Zheng S Lewis

A comparative analysis of the genomes of Drosophila melanogaster, Caenorhabditis elegans, and Saccharomyces cerevisiae-and the proteins they are predicted to encode-was undertaken in the context of cellular, developmental, and evolutionary processes. The nonredundant protein sets of flies and worms are similar in size and are only twice that of yeast, but different gene families are expanded in...

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