An age replacement maintenance policy is considered here, in which a system is restored whenever it fails, or ages without failure up to a preventive maintenance epoch (whichever comes first). The duration of the restoration activity is random, and depends on whether it was precipitated by a failure or by a preventive maintenance action. The case where the preventive maintenance epoch is determ...

This paper develops an effective joint production, setup and maintenance control policies in an unreliable one-machine two-products manufacturing system. The main objective is to reach a higher synchronization level of the preventive maintenance (PM) interventions in the planning of production activities. The proposed joint control policy integrates the concept of the opportunistic maintenance ...

This paper introduces a modular modeling approach for distributed production systems, considering production and maintenance processes synchronization. Thus, production job shop, preventive and curative specialized telemaintenance actions are studied together. Stochastic synchronized Petri nets are used for modeling. This tool was adapted to the tele/maintenance distributed case and to integrat...

Ischemic heart disease (IHD) has been linked to exposures to airborne particles with an aerodynamic diameter <2.5 μm (PM2.5) in the ambient environment and in occupational settings. Routine industrial exposure monitoring, however, has traditionally focused on total particulate matter (TPM). To assess potential benefits of PM2.5 monitoring, we compared the exposure-response relationships between...

This paper presents the stochastic analysis of a two unit parallel system model with the concept of correlation between time to preventive maintenance and preventive maintenance time. The joint distribution of time to preventive maintenance and preventive maintenance time is taken bivariate exponential. Using regenerative point technique, various measures of system effectiveness useful to syste...

Monoclonal antibodies (TpM 3, TpM 6, and TpM 19) against Toxoplasma gondii insoluble antigens were produced by the hybridization of NS-1, a mouse myeloma cell line, with spleen cells from mice immunized with T. gondii insoluble antigens. TpM 3, TpM 6, and TpM 19 were characterized by the dye test, the latex agglutination test, two types of enzyme-linked immunosorbent assays, using either T. gon...

We show that Topiramate (TPM) treatment normalizes whole body insulin sensitivity in high-fat diet (HFD)-fed male Wistar rats. Thus drug treatment markedly lowered glucose and insulin levels during glucose tolerance tests and caused increased insulin sensitization in adipose and muscle tissues as assessed by euglycemic clamp studies. The insulin-stimulated glucose disposal rate increased twofol...

Background Magnetic resonance (MR) imaging has become an important diagnostic tool for the detection of impaired myocardial motion, which has been considered as a common consequence of most ischemic or non-ischemic heart diseases. Both cine DENSE and TPM have been independently adopted to delineate abnormal regional myocardial motion patterns for the estimation of the progression of cardiovascu...

Given recent increases in global competition, scarce resources, and fluctuating economies, it is not surprising that lean production has become critical to the long-term survival of today’s manufacturing organizations. Lean is a management philosophy focused on identifying and eliminating waste throughout a product’s entire value stream, extending not onlywithin theorganization but also along t...