نتایج جستجو برای: evolution transcriptomics
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The molecular genetic program for root hair development has been studied intensively in Arabidopsis (Arabidopsis thaliana). To understand the extent to which this program might operate in other plants, we conducted a large-scale comparative analysis of root hair development genes from diverse vascular plants, including eudicots, monocots, and a lycophyte. Combining phylogenetics and transcripto...
Characterized by distinctive evolutionary adaptations, spiders provide a comprehensive system for evolutionary and developmental studies of anatomical organs, including silk and venom production. Here we performed cDNA sequencing using massively parallel sequencers (454 GS-FLX Titanium) to generate ∼80,000 reads from the spinning gland of Actinopus spp. (infraorder: Mygalomorphae) and Gasteraca...
کاربرد موفقیت آمیز مدل های بارش – رواناب، به چگونگی واسنجی پارامترهای آنها بستگی دارد. مدل های مفهومی بارش - رواناب، عموماً دارای پارامترهای زیادی هستند که نمی توان آنها را به صورت مستقیم برآورد نمود و لازم است که آنها را در طول واسنجی مدل تخمین زد. هدف از انجام واسنجی، یافتن مقادیر آن سری از پارامترهایی است که باعث بهینه شدن معیارهای ارزیابی کارایی مدل می شوند. دو روش دستی و خودکار برای واسنجی ...
Omics is becoming a comprehensive approach to study the molecules in living organisms. In this paper, the progress of research in tree genomics, transcriptomics, proteomics, metabolomics and other biotechnologies in China is summarized. Genomics, including functional genomics, structural genomics and comparative genomics, have been studied since the 1990s and some important achievements have be...
Transcriptomics is a powerful tool for elucidating the molecular mechanisms that underlie the ability of organisms to survive and thrive in dynamic and changing environments. Here, we review the major contributions in this field, and we focus on studies of mussels in the genus Mytilus, which are well-established models for the study of ecological physiology in fluctuating environments. Our revi...
UNLABELLED With the advent of next-generation sequencing, -omics fields such as transcriptomics have experienced increases in data throughput on the order of magnitudes. In terms of analyzing and visually representing these huge datasets, an intuitive and computationally tractable approach is to map quantified transcript expression onto biochemical pathways while employing datamining and visual...
The ability to sequence whole genomes has taught us that our knowledge with respect to gene function is rather limited with typically 30-40% of open reading frames having no known function. Thus, within the life sciences there is a need for determination of the biological function of these so-called orphan genes, some of which may be molecular targets for therapeutic intervention. The search fo...
In our previous study, a new compound, octadecanoic acid-3, 4-tetrahydrofuran diester, possessing potent acaricidal activity was obtained from neem oil. This study performed RNA-seq transcriptomics and iTRAQ proteomics to uncover the acaricidal mechanism of the compound against Sarcoptes scabiei var. cuniculi. The results of transcriptomics indicated that after treatment with octadecanoic acid-...
RNA-seq is being used increasingly for gene expression studies and it is revolutionizing the fields of genomics and transcriptomics. However, the field of RNA-seq analysis is still evolving. Therefore, we specifically designed this study to contain large numbers of reads and four biological replicates per condition so we could alter these parameters and assess their impact on differential expre...
Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β (Aβ). The genes that govern this process, however, have remained elusive. To this end, we combined distinct mouse strains with transcriptomics to directly identify disease-relevant genes. We show that AD model mice (APP-Tg) with DBA/2 genetic backgrounds have significantly lower levels of Aβ accumulation compared with SJ...
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