OBJECTIVE To confirm or refute the notion that only parathyroid adenomas have radioactivity higher than 20% of background. DESIGN Retrospective analysis of a prospective patient data set. SETTING Tertiary care referral center. PATIENTS Forty-six patients (9 men and 37 women; mean +/- SD age, 53.7 +/- 12.1 years) underwent thyroid and parathyroid surgery between December 2005 and December ...

PURPOSE To establish a method for assessing graft viability, in-vivo, following corneal transplantation. METHODS Optimization of calcein AM fluorescence and toxicity assessment was performed in cultured human corneal endothelial cells and ex-vivo corneal tissue. Descemet membrane endothelial keratoplasty grafts were incubated with calcein AM and imaged pre and post preparation, and in-situ af...

Confocal microscopy is an imaging tool that uses a laser system to image the skin noninvasively with cellular resolution. With both in vivo and ex vivo systems, tissue can be imaged rapidly without damaging the sample. Herein, we discuss the capabilities of the ex vivo confocal microscope and its implementation for treatment and management of cutaneous malignancies.

Allogeneic stem cell transplantation with umbilical cord blood (UCB) cells is limited by the cell dose a single unit provides recipients. Ex vivo expansion is one strategy to increase the number of cells available for transplantation. Aastrom Biosciences developed an automated continuous perfusion culture device for expansion of hematopoietic stem cells (HSCs). Cells are expanded in media suppl...