Background and objectives: Dorema ammoniacum gum resin is used in Iranian traditional medicine for different indications including inflammatory diseases which are on the rise. Considering the important role of inflammation in different diseases, in the present study, we aimed to investigate the in vivo anti-inflammatory activity and skin toxicity of Dorema ammoniac...

malvastrum tricuspidatum is recommended in ayurveda and folklore medicine for the management of gastric ulcers. therefore, the purpose of the study was to investigate the antiulcer effect of whole plant extract of malvastrum tricuspidatum (mte) on ethanol (etoh)-induced, aspirin (asp)-induced, cold-restraint-stress (cru) and pylorus--ligation(pl)-induced gastric ulcer models in rats. aqueous ex...

in the present study, the effects of pregnant nmri mice restraint stress on the responsibility of their children to the behavioral properties of morphine, sulpiride and dextromethorphan were investigated in the f2 generation. twenty four pregnant nmri female mice (w: 25 g) were divided into the experimental and control groups (n = 12/group). animals in the experimental group were kept in the re...

The minimal lethal dose of methanol in humans has not been determined. It has been suggested that about I g kg can cause death if the patient is untreated and has not consumed ethanol.43 In some clinical cases, the blood methanol content is low in the last phase of the poisoning. In three such cases blood methanol concentration was 0.275,_0.277. and 0.194 gi , respectively. On the assumption th...

Obesity its only possible origin is off the plate. It is a question of imbalance between food intake and energy expenditure. Since food intake is regulated by appetite, Dr Morrison’s paper is pertinent. The treatment of obesity is largely a problem for dietetic practice, and it is fitting that Miss Rose should conclude this Symposium with an account of her unrivalled experience in this field. O...

Conditions for extrapolating toxicologic data from animals to man were studied. In the search for general regularities associated with the comparative sensitivity of humans and various species of animals to toxins, it was shown that the toxicity parameters of compounds and the biological constants of mammals correlate with body weight. This relationship is well described by a rectilinear regres...

BACKGROUND The incidence of kidney diseases is increasing worldwide and they are emerging as a major public health problem. Once mostly considered inexorable, renal disease progression can now be halted and lesions can even regress with drugs such as angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II type I receptor blockers, indicating the possibility of kidney repair. SUMMAR...