نتایج جستجو برای: experimental autoimmune vitiligo
تعداد نتایج: 764305 فیلتر نتایج به سال:
The Smyth line (SL) of chicken is an excellent animal model for human autoimmune vitiligo. In SL vitiligo (SLV), postnatal loss of melanocytes in feathers appears to be due to cell-mediated immunity. In this study, leukocyte infiltration and associated expression (RNA) of immune function-related cytokines in growing feathers were investigated throughout SLV development and progression. Both leu...
Melanocyte differentiation Ags, including tyrosinase-related protein (TRP) 1, are relevant to both autoimmune skin depigmentation (vitiligo) and tumor immunity, because they are expressed by both benign melanocytes and many malignant melanomas. Melanoma patients generate CD4(+) T cells that specifically recognize these proteins. TRP1 contains internal disulfide bonds and is presented by MHC cla...
BACKGROUND The members of Toll-like receptor (TLR) family are responsible for recognizing various molecular patterns associated with pathogens. Their expression is not confined to immune cells and have been detected in skin cells such as keratinocytes and melanocytes. As part of a generated response to pathogens, TLRs are involved in inducing inflammatory mediators to combat these threats. It i...
Vitiligo is a melanocytic disorder that diagnosed by depigmented skin patches and hairs that may appear with neuro-ophthalmo-labyrintic involvement . Association with some other autoimmune disorders such as diabetes,thyroiditis and gastric parietal cells antibody has been observed. &n...
Background & Aim: Vitiligo is a common skin disorder with unknown origin. An increased prevalence of autoimmune diseases, including thyroid diseases, has been described in patients with vitiligo. The aim of this study was to assess the prevalence of thyroid dysfunction and hypoparathyroidism in patients with vitiligo. Patients and Method: One hundred and nine patients(38 males & 71 females)...
OBJECTIVE To compare factors associated with halo nevi with nonsegmental vitiligo (NSV) vs NSV alone. DESIGN Prospective observational study in 553 patients with a confirmed diagnosis of NSV attending a vitiligo clinic between January 1, 2006, and July 1, 2010. SETTING Vitiligo Clinic at the Department of Dermatology, University Hospital Center of Bordeaux, Bordeaux, France. PATIENTS The ...
Vitiligo is one of the most well-known conditions of skin depigmentation. It is estimated to occur in up to 2% of the world’s population. A number of people, these patches can prove all over the body. It is an autoimmune disease in which the pigmentinducing cells are injured. There is no therapy for vitiligo, however there are few therapies, including ultraviolet light, cosmetic cover-ups or co...
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