A great deal is known about the export of spliced mRNAs, but little is known about the export of mRNAs encoded by human cellular genes that naturally lack introns. Here, we investigated the requirements for export of three naturally intronless mRNAs (HSPB3, IFN-α1, and IFN-β1). Significantly, we found that all three mRNAs are stable and accumulate in the cytoplasm, whereas size-matched random R...

The eukaryotic translation initiation factor 4E (eIF4E) controls gene expression through its effects on mRNA export and cap-dependent translation, both of which contribute to its oncogenic potential. In contrast to its translation function, the mRNA export function of eIF4E is poorly understood. Using an RNP isolation/mass spectrometry approach, we identified candidate cofactors of eIF4E mRNA e...

The mechanism of mRNA export is a complex issue central to cellular physiology. We characterized previously yeast Gle1p, a protein with a leucine-rich (LR) nuclear export sequence (NES) that is essential for poly(A)+ RNA export in Saccharomyces cerevisiae. To characterize elements of the vertebrate mRNA export pathway, we identified a human homologue of yeast Gle1p and analyzed its function in ...

Ribose-binding protein (RBP) is exported to the periplasm of Escherichia coli via the general export pathway. An rbsB-lacZ gene fusion was constructed and used to select mutants defective in RBP export. The spontaneous Lac+ mutants isolated in this selection contained either single-amino-acid substitutions or a deletion of the RBP signal sequence. Intact rbsB genes containing eight different po...

This study examines the impact of the Internet, firm-specific characteristics, market characteristics, and export marketing strategy on export marketing performance. The unit of analysis was an individual product/market export venture. Data were gathered via a self-administered mail survey of 315 Australian firms involved in exporting. The findings indicate that when the Internet was used for c...

Siam citrus is a potential horticultural commodity for export and has high economic value. This research was conducted in Umbulsari District, Jember Regency, one of the productions marketing centres East Java Province. The results on production system Regency show that economically agribusiness provides direct benefits to local farmers multiplier effect household. been running, involving many a...

The increased in global demand for natural rubber commodities opens opportunities exporting countries to compete with their competitors. Competitiveness is the main provision be able well. Therefore, this research was conducted determine export competitiveness of by and position commodity each exporter market. data were secondary sourced from Trademap period 2001-2019. Furthermore, analyzed usi...

The estimation resulted through the combination of ECM and WLS shows that the price of export goods/merchandises has a positive effect and is significant in the short-term period. Yet, over the longterm period, the increase in export commodity price causes the decrease in export volumes. Meanwhile, the relationship between export volume and inflation is not significant, either in the short-term...

This paper examines the horizontal and vertical export spillovers of foreign direct investment (FDI) on China’s manufacturing domestic firms by using firm-level census data over the period of 2000–03. Based on a Heckman two-step procedure combining first differencing and instrumental variable regression techniques, we find that FDI has had a positive impact on the export value of domestic firms...

In this paper we investigated the hypothesis of export spillovers from foreign multinationals to domestic firms using a data set of UK manufacturing firms from 1992 to 1999. Unlike previous studies we allow not only for the possibility of horizontal (i.e. intraindustry) and regional externalities, but also for vertical ones (i.e. inter-industry: forward and backward). Deploying and Heckman sele...