Nosocomial infections caused by extended-spectrum beta-lactamase (ESBL)-producing gram-negative bacteria complicate therapy and limit treatment options. However, the clinical significance of infections caused by ESBL-producing bacteria remains unclear. A critical examination of the literature provides divergent views of the effect of ESBL carriage on morbidity and mortality and suggests that ES...

Klebsiella pneumoniae is a pathogen primarily capable of causing urinary tract infections and pneumonia in otherwise healthy people. Most of the strains are frequently resistant to numerous antibiotics, responsible for conferring multidrug resistance. This study was conducted to determine the prevalence of extended spectrum β-lactamases (ESBL), AmpC β-lactamases and metallo β-lactamases (MBL) a...