BACKGROUND Biochemical control from series in which radical prostatectomy is performed for patients with unfavorable prostate cancer and/or low dose external beam radiation therapy are given remains suboptimal.The treatment regimen of HDR brachytherapy and external beam radiotherapy is a safe and very effective treatment for patients with high risk localized prostate cancer with excellent bioch...

OBJECTIVE To develop a consensus-based guideline to define clinical target volume for primary disease (clinical target volume primary) in external beam radiotherapy for intact uterine cervical cancer. METHODS The working subgroup of the JCOG Radiation Therapy Study Group began developing a guideline for primary clinical target volume in November 2009. The group consisted of 10 radiation oncol...

Introduction: Radical laryngeal surgeries for extensive laryngeal and hypopharyngeal tumors often require a permanent tracheostomy, which has an immense impact on the quality of life of patients. A minimally invasive technique such as transoral laser microresection (TLM) followed by radiotherapy can preserve the functions of the voice and swallowing. The aim of this study is to evaluate the ro...

Hemorrhagic gastritis is a possible late toxicity outcome after radical radiotherapy but it is nowadays a very rare condition and most likely depends on other clinical factors. We report the case of a 77-year-old woman with a symptomatic solitary extramedullary intra-abdominal plasmacytoma and multiple gastric comorbidities, treated with external beam radiotherapy. Despite the good response to ...

PURPOSE Genetic radiotherapy, the combination of gene therapy and radiation therapy, for cancer treatment is evolving from laboratory studies to clinical trials. Genetic radiotherapy involves the viral infection of cells that change the sensitivity of transduced cells to radiation. Because there is no patient outcome data for genetic radiotherapy, prospective models are needed to determine the ...

"Stereotactic" is an exact radiotherapy treatment modality which implements invasive and non-invasive facilities for improving precise dose delivery. Stereotactic refers to three-dimensional localization of a specific point in space by a unique set of coordinates that relate to a fixed external reference frame. An accurate delivery of radiation is attainable using these techniques with high pre...

This clinical practice guideline is a set of evidence-based recommendations to assist radiographers, radiotherapy nurses, and the wider radiotherapy workforce, in advising patients how to care for their skin while undergoing a course of radical external beam radiotherapy (excluding proton therapy). It has been developed systematically using the best available evidence from research and expert o...

This clinical practice guideline is a set of evidence-based recommendations to assist radiographers, radiotherapy nurses, and the wider radiotherapy workforce, in advising patients how to care for their skin while undergoing a course of radical external beam radiotherapy (excluding proton therapy). It has been developed systematically using the best available evidence from research and expert o...

Breast conserving surgery (BCS) with postoperative radiotherapy has been a standard treatment of early stage breast cancer for the last 30 years. Interstitial brachytherapy has been used as a boost therapy after whole breast external beam radiotherapy (EBRT), and recently, it's been investigated in selected patients as a possible technique of a single radiotherapy modality (partial breast irrad...