Periodontitis is an inflammatory disease of the oral cavity initiated by a microbial biofilm (or 'dental plaque'). Subgingival biofilms in periodontal pockets are not easily analyzed without the loss of structural integrity. These subgingival plaques are structured communities of microorganisms with great phylogenetic diversity embedded in a self-produced extracellular polymeric matrix. For alm...

Polymeric carriers may deliver therapeutic substances and biomolecules to the destination place in unchanged form. Their use in the therapy of solid tumors in comparison to unbound drugs brings about several benefits, such as drug dose reduction as well as adverse effects decrease. The primary advantage of the described conjugates is the control release of the pharmacologically or biologically ...

Complexity of bacterial biofilms is generally due to their composition in terms of microorganisms as well as in the diversity of their matrix components. The commonly described extracellular polymeric substances (EPS) are exopolysaccharides (ePS), exoproteins (ePN) and extracellular DNA (eDNA). Besides, several studies have shown that the ePN are the most abundant compound within a biofilm [1]....